Encontrados 21 documentos, a visualizar página 1 de 3
Brazilian guidelines for the pharmacological treatment of idiopathic pulmonary ...
Baddini-Martinez,José; Ferreira,Juliana; Tanni,Suzana; Alves,Luis Renato; Cabral Junior,Benedito Francisco; Carvalho,Carlos Roberto RibeiroABSTRACT Idiopathic pulmonary fibrosis (IPF) is a form of chronic interstitial lung disease of unknown cause, which predominantly affects elderly men who are current or former smokers. Even though it is an uncommon disease, it is of great importance because of its severity and poor prognosis. In recent decades, several pharmacological treatment modalities have been investigated for the treatment of this disease...
Characterization and outcomes of pulmonary alveolar proteinosis in Brazil: a ca...
Athayde,Rodolfo Augusto Bacelar de; Arimura,Fábio Eiji; Kairalla,Ronaldo Adib; Carvalho,Carlos Roberto Ribeiro; Baldi,Bruno GuedesABSTRACT Objective: Pulmonary alveolar proteinosis (PAP) is a rare disease, characterized by the alveolar accumulation of surfactant, which is composed of proteins and lipids. PAP is caused by a deficit of macrophage activity, for which the main treatment is whole-lung lavage (WLL). We report the experience at a referral center for PAP in Brazil. Methods: This was a retrospective study involving patients with P...
Hard metal lung disease: a case series
Mizutani,Rafael Futoshi; Terra-Filho,Mário; Lima,Evelise; Freitas,Carolina Salim Gonçalves; Chate,Rodrigo Caruso; Kairalla,Ronaldo AdibABSTRACT Objective: To describe diagnostic and treatment aspects of hard metal lung disease (HMLD) and to review the current literature on the topic. Methods: This was a retrospective study based on the medical records of patients treated at the Occupational Respiratory Diseases Clinic of the Instituto do Coração, in the city of São Paulo, Brazil, between 2010 and 2013. Results: Of 320 patients treated during t...
Lung-dominant connective tissue disease among patients with interstitial lung d...
Pereira,Daniel Antunes Silva; Dias,Olívia Meira; Almeida,Guilherme Eler de; Araujo,Mariana Sponholz; Kawano-Dourado,Letícia Barbosa; Baldi,Bruno GuedesOBJECTIVE: To describe the characteristics of a cohort of patients with lung-dominant connective tissue disease (LD-CTD). METHODS: This was a retrospective study of patients with interstitial lung disease (ILD), positive antinuclear antibody (ANA) results (≥ 1/320), with or without specific autoantibodies, and at least one clinical feature suggestive of connective tissue disease (CTD). RESULTS: Of the 1,998 pat...
Use of sirolimus in the treatment of lymphangioleiomyomatosis: favorable respon...
Freitas,Carolina Salim Gonçalves; Baldi,Bruno Guedes; Araújo,Mariana Sponholz; Heiden,Glaucia Itamaro; Kairalla,Ronaldo AdibOBJECTIVE: Lymphangioleiomyomatosis (LAM) is a rare disease that is currently considered a low-grade neoplasm with metastatic potential and variable progression. Mammalian target of rapamycin (mTOR) inhibitors, such as sirolimus and everolimus, have recently become a treatment option for LAM patients, especially those with extrapulmonary manifestations. The objective of the present study was to describe a case ...
Pulmonary involvement in rheumatoid arthritis: evaluation by radiography and sp...
Kawassaki,Alexandre Melo; Pereira,Daniel Antunes Silva; Kay,Fernando Uliana; Laurindo,Ieda Maria Magalhães; Carvalho,Carlos Roberto RibeiroAbstractObjective: To determine whether simple diagnostic methods can yield relevant disease information in patients with rheumatoid arthritis (RA).Methods: Patients with RA were randomly selected for inclusion in a cross-sectional study involving clinical evaluation of pulmonary function, including pulse oximetry (determination of SpO2, at rest), chest X-ray, and spirometry.Results: A total of 246 RA patients ...
Lymphadenopathy and fever in a chef during a stay in Europe
Kawano-Dourado,Letícia; Peirera,Daniel Antunes Silva; Kawassaki,Alexandre de Melo; Dolhnikoff,Marisa; Silva,Marcos Vinicius da; Kairalla,Ronaldo AdibThis case illustrates a rare presentation (as lymphadenopathy and fever) of one of the most common zoonotic diseases worldwide-brucellosis-in a 22-year-old Brazilian male (a chef) who had recently returned to Brazil after having lived in and traveled around Europe for one year. The histopathology, clinical history, and response to treatment were all consistent with a diagnosis of brucellosis, which was confirme...
Recomendações brasileiras de ventilação mecânica 2013. Parte I
Barbas,Carmen Sílvia Valente; Ísola,Alexandre Marini; Farias,Augusto Manoel de Carvalho; Cavalcanti,Alexandre Biasi; Gama,Ana Maria CasatiO suporte ventilatório artificial invasivo e não invasivo ao paciente crítico tem evoluído e inúmeras evidências têm surgido, podendo ter impacto na melhora da sobrevida e da qualidade do atendimento oferecido nas unidades de terapia intensiva no Brasil. Isto posto, a Associação de Medicina Intensiva Brasileira (AMIB) e a Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) - representadas pelo seus Comitê d...
Recomendações brasileiras de ventilação mecânica 2013. Parte 2
Barbas,Carmen Sílvia Valente; Ísola,Alexandre Marini; Farias,Augusto Manoel de Carvalho; Cavalcanti,Alexandre Biasi; Gama,Ana Maria CasatiO suporte ventilatório artificial invasivo e não invasivo ao paciente grave tem evoluído e inúmeras evidências têm surgido, podendo ter impacto na melhora da sobrevida e da qualidade do atendimento oferecido nas unidades de terapia intensiva no Brasil. Isto posto, a Associação de Medicina Intensiva Brasileira (AMIB) e a Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) - representadas por seu Comitê de Ve...
Adalimumab-induced acute interstitial lung disease in a patient with rheumatoid...
Dias,Olivia Meira; Pereira,Daniel Antunes Silva; Baldi,Bruno Guedes; Costa,Andre Nathan; Athanazio,Rodrigo Abensur; Kairalla,Ronaldo AdibThe use of immunobiological agents for the treatment of autoimmune diseases is increasing in medical practice. Anti-TNF therapies have been increasingly used in refractory autoimmune diseases, especially rheumatoid arthritis, with promising results. However, the use of such therapies has been associated with an increased risk of developing other autoimmune diseases. In addition, the use of anti-TNF agents can c...