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The Porto European Cancer Research Summit 2021

Ringborg, U; Berns, A; Celis, JE; Heitor, M; Tabernero, J; Schüz, J; Baumann, M; Henrique, R; Aapro, M; Basu, P; Beets-Tan, R; Besse, B; Cardoso, F

Key stakeholders from the cancer research continuum met in May 2021 at the European Cancer Research Summit in Porto to discuss priorities and specific action points required for the successful implementation of the European Cancer Mission and Europe's Beating Cancer Plan (EBCP). Speakers presented a unified view about the need to establish high-quality, networked infrastructures to decrease cancer incidence, in...


Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratifi...

Bruun, J; Sveen, A; Barros, R; Eide, P; Eilertsen, I; Kolberg, M; Pellinen, T; David, L; Svindland, A; Kallioniemi, O; Guren, M; Nesbakken, A

We aimed to refine the value of CDX2 as an independent prognostic and predictive biomarker in colorectal cancer (CRC) according to disease stage and chemotherapy sensitivity in preclinical models. CDX2 expression was evaluated in 1045 stage I–IV primary CRCs by gene expression (n = 403) or immunohistochemistry (n = 642) and in relation to 5-year relapse-free survival (RFS), overall survival (OS), and chemothera...


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