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Efects of açai on oxidative stress, ER stress, and infammationrelated parameter...

Carvalho, Mayara Medeiros de Freitas; Lage, Nara Nunes; Paulino, Alice Helena de Souza; Pereira, Renata Rebeca; Almeida, Letícia Trindade

Non-alcoholic fatty liver disease (NAFLD), the most predominant liver disease worldwide, is a progressive condition that encompasses a spectrum of disorders ranging from steatosis to steatohepatitis, and, ultimately, cirrhosis and hepatocellular carcinoma. Although the underlying mechanism is complex and multifactorial, several intracellular events leading to its progression have been identified, including oxid...

Date: 2020   |   Origin: Oasisbr

Açai improves non-alcoholic fatty liver disease (NAFLD) induced by fructose.

Carvalho, Mayara Medeiros de Freitas; Reis, Larissa Lélis Teixeira; Lopes, Juliana Márcia Macedo; Lage, Nara Nunes; Guerra, Joyce Ferreira da Costa

Introduction: the excessive consumption of fructose can cause liver damage, characteristic of non-alcoholic fatty liver disease (NAFLD) associated with changes in lipid metabolism and antioxidant defenses. Açai, the fruit of Euterpe oleracea Mart., has demonstrated numerous biological activities, including anti-inflammatory, antioxidant, and lipid metabolism modulating action. Objective: we evaluated the benefi...

Date: 2019   |   Origin: Oasisbr

Hydroalcoholic extract of Brazilian green propolis modulates inflammatory proce...

Miranda, Marina Barcelos de; Lanna, Mariana Ferreira; Nascimento, Ana Luiza Barros; Paula, Carmen Aparecida de; Silva, Marcelo Eustáquio

The occurrence of inflammation and protein malnutrition is an aggravating risk factor for morbidity and mortality in the clinical setting. The green propolis, a natural product made by Apis mellifera bees from Baccharis dracunculifolia resin, has therapeutic potential to modulate chronic inflammation. However, its effect on inflammation in an impaired nutritional status is not known. The aim of this study was t...

Date: 2019   |   Origin: Oasisbr

Physical exercise improves body weight gain and liver function in malnourished ...

Oliveira, Emerson Cruz de; Santos, Rinaldo Cardoso dos; Oliveira, Lenice Kappes Becker; Coelho, Daniel Barbosa; Pedrosa, Maria Lúcia

Objective To study the relationship between exercise and malnourishment because recent evidence suggests that exercise can cause the benefi cial adaptation of antioxidant systems, whereas malnourishment can cause harmful adaptation of these systems. Methods Thirty-two female Fischer rats were equally divided into Sedentary Control, Trained Control, Sedentary Malnourished and Trained Malnourished groups. The tra...

Date: 2019   |   Origin: Oasisbr

Baccharis trimera (Carqueja) Improves metabolic and redox status in an experime...

Kaut, Natália Nogueira do Nascimento; Rabelo, Ana Carolina Silveira; Araújo, Glaucy Rodrigues de; Taylor, Jason Guy; Silva, Marcelo Eustáquio

Diabetes mellitus is a metabolic disorder that causes severe complications due to the increased oxidative stress induced by disease. Many plants are popularly used in the treatment of diabetes, e.g., Baccharis trimera (carqueja). The aim of this study was to explore the potential application of the B. trimera hydroethanolic extract in preventing redox stress induced by diabetes and its hypoglycemic properties. ...

Date: 2019   |   Origin: Oasisbr

Araçá (Psidium cattleianum Sabine) ameliorates liver damage and reduces hepatic...

Paulino, Alice Helena de Souza; Viana, Ana Maria Fernandes; Bonomo, Larissa de Freitas; Guerra, Joyce Ferreira da Costa; Lopes, Juliana Márcia Macedo

Bioactive compounds, present in some foods, act enhancing the endogenous antioxidant system and are proposed as an effective strategy in preventing the changes induced by free radicals in some diseases, such as nonalcoholic fatty liver disease (NAFLD). There has been an increase in the number of studies carried out with the aim of finding natural antioxidant compounds present in fruits, mainly the native fruits...

Date: 2019   |   Origin: Oasisbr

Biodegradable seeds of holmium don´t change neurological function after implant...

Diniz, Mirla Fiuza; Ferreira, Diogo Milioli; Lima, Wanderson Geraldo de; Pedrosa, Maria Lúcia; Silva, Marcelo Eustáquio; Araujo, Stanley de Almeida

Aim: To evaluate the surgical procedure and parenchymal abnormalities related to implan-tation of ceramic seeds with holmium-165 in rats’ brain.Background: An effective method of cancer treatment is brachytherapy in which radioactiveseeds are implanted in the tumor, generating a high local dose of ionizing radiation thatcan eliminate tumor cells while protecting the surrounding healthy tissue. BiodegradableHo16...

Date: 2018   |   Origin: Oasisbr

Lipid profile of malnourished and nutritionally recovered trained and sedentary...

Oliveira, Emerson Cruz de; Santos, Rinaldo Cardoso dos; Pedrosa, Maria Lúcia; Silva, Marcelo Eustáquio

The goal of this work was to verify whether malnutrition causes modifications in lipid profile and if nutritional recovery associated or not with exercise (swimming, 30 minutes/day, five days/week during 8 weeks) can interfere in this process. Fifty two Fisher female rats were divided into six groups: Control sedentary (CS), control trained (CT), recovered sedentary (RS), malnourished sedentary (MS) and malnour...

Date: 2017   |   Origin: Oasisbr

Efect of physical exercise on HDL/LDL ratio, protein metabolism and bones in ra...

Gonçalves, Allan Cristian; Faria, Wanda Maria de; Pedrosa, Maria Lúcia; Silva, Marcelo Eustáquio

The correct characterization of hypercholesterolemic models involves the knowledge of the effect of diet on parameters the go beyond lipid metabolism and that nevertheless reflect the effect of the hypercholesterolemic diet on the development of the animals. Equally important, the exact notion of the magnitude of the stress provoked by physical training helps the understanding of its effect on the objects of in...

Date: 2017   |   Origin: Oasisbr

Study of the hepatic function of exercised and nutritionally recovered animals.

Oliveira, Emerson Cruz de; Santos, Rinaldo Cardoso dos; Pedrosa, Maria Lúcia; Silva, Marcelo Eustáquio

The goal of the present work was to study the hepatic function of animals in a process of nutritional recovery associated or not with physical exercise (swimming 30 minutes/day during 8 weeks). Fifty two female Fisher rats were divided into six groups: Control Sedentary (CS), Control Trained (CT), Recovered Sedentary (RS), Recovered Trained (RT), Malnourished Sedentary (MS) and Malnourished Trained (MT). We hav...

Date: 2017   |   Origin: Oasisbr

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