2 documents found, page 1 of 1
Xanthones for melanogenesis inhibition : Molecular docking and QSAR studies to ...
Rosa, Gonçalo P.; Palmeira, A.; Resende, Diana I. S. P.; Almeida, Isabel F.; Kane-Pagès, Aida; Barreto, Maria do Carmo; Sousa, E.; Pinto, Madalena M. M.The human skin is constantly exposed to external factors that affect its integrity, UV radiation being one of the main stress factors. The repeated exposure to this radiation leads to increased production of Reactive Oxygen Species (ROS) which activate a series of processes involved in photoaging. Excessive UV exposure also exacerbates melanin production leading to a variety of pigmentation disorders. Xanthones...
Efficacy, Stability, and Safety Evaluation of New Polyphenolic Xanthones Toward...
Resende, Diana I. S. P.; Almeida, Mariana C.; Maciel, Bruna; Carmo, Helena; Lobo, José Sousa; Dal Pozzo, Carlotta; Cravo, Sara M.; Rosa, Gonçalo P.Antioxidants have long been used in the cosmetic industry to prevent skin photoaging, which is mediated by oxidative stress, making the search for new antioxidant compounds highly desirable in this field. Naturally occurring xanthones are polyphenolic compounds that can be found in microorganisms, fungi, lichens, and some higher plants. This class of polyphenols has a privileged scaffold that grants them severa...