13 documents found, page 1 of 2
Fitoterápicos de plantas medicinais do bioma amazônico e Cerrado em abordagem a...
Kanzaki, Luis Isamu Barros; Mata, Élida Cleyse Gomes da; Silva, Joaquim Xavier da; Ornelas, Sócrates Souza; Silva, Breno Marques Silva eEm face da constante emergência e reemergência de patógenos virais, como no momento atual por SARS-CoV-2, a terapia da COVID-19 tem sido polêmica. Vacinas anti-SARS-CoV-2 estão em desenvolvimento, mas a eficácia e segurança são discutíveis. Raras exceções, os fármacos são obtidos de produtos naturais ou tem sua imagem química em base ao que a natureza nos proporciona, assim que, continua--se a prospecção na bio...
Replica??o de sendai virus em c?lulas epiteliais prim?rias de camundongo
Kanzaki, Luis Isamu BarrosMinist?rio da Sa?de. Funda??o Servi?os de Sa?de P?blica. Instituto Evandro Chagas. Bel?m, PA, Brasil.; C?lulas epiteliais prim?rias obtidas do trato respirat?rio de camundongos jovens foram infectadas com o V?rus Hemaglutinante do Jap?o (HVJ, Sendai Virus) e, a prog?nie viral, tratada ou n?o com tripsina foi titulada atrav?s do m?todo de Imunofluoresc?ncia Indireta. A prog?nie de Sendai Virus obtida de c?lulas ...
Characterization of Aspergillus species on Brazil nut from the Brazilian Amazon...
Midorikawa, Gláucia Emy Okida; Sousa, Maria de Lourdes M. de; Silva, Otniel Freitas; Dias, Jurema do Socorro A.; Kanzaki, Luis Isamu BarrosBackground: Brazil nut is a protein-rich extractivist tree crop in the Amazon region. Fungal contamination of shells and kernel material frequently includes the presence of aflatoxigenic Aspergillus species from the section Flavi. Aflatoxins are polyketide secondary metabolites, which are hepatotoxic carcinogens in mammals. The objectives of this study were to identify Aspergillus species occurring on Brazil nu...
Aerobic and facultative microorganisms isolated from corroded metallic structur...
Correia, Amabel Fernandes; Segoviae, Jorge Federico Orellana; Bezerra, Roberto Messias; Gonçalves, Magda Celeste Alvares; Ornelas, Sócrates SouzaAerobic and facultative bacteria belonging to the Enterobacteriaceae, Pseudomonadaceae, Bacillaceae, Corynebacteriaceae and Streptococcaceae families have been isolated from corroded metallic structures of a hydroelectric power unit in the Amazon region of Brazil. In addition to anamorphic dematiaceous and moniliaceous fungi, members of the archeobacteria kingdom were also detected in the same samples. Scanning...
Prevalence of human T cell leukemia virus-I (HTLV-I) antibody among populations...
Nakauchi, C.M.; Linhares, Alexandre da Costa; Maruyama, Koshi; Kanzaki, Luis Isamu Barros; Macedo, J. E.; Azevedo, Vânia NakauthABSTRACT; Forty-tree (31.4%) out of 137 serum samples obtained from two Indian communities living in the Amazon region were found to be positive for HTLV-I antibody, as tested by enzyme-linked immunosorbent assay (Elisa). Eighty-two sera were collected from Mekranoiti Indians, yielding 39% of positivity, whereas 11 (20.0%) or the 55 Tiriyo serum samples had antibody to HTLV-I. In addition, positive results occu...
Prevalence of HTLV-I antibody among two distinct ethnic groups inhabiting the A...
Nakauchi, C.M.; Maruyama, Koshi; Kanzaki, Luis Isamu Barros; Linhares, Alexandre da Costa; Azevedo, Vânia Nakauth; Fukushima, T.; Miyauchi, M.Soroprevalências para HTLV-I de 3,63% (02/55), 12,9% (10/82) e 13,88% (10/72) foram demonstradas entre os Tiryió, Mekranoiti e Xicrin, respectivamente - indígenas habitantes da Amazônia -, utilizando-se a técnica de "Western Blot" (WBEI). Por outro lado, a imunomicroscopia eletrônica indireta (IIME) revelou como positivos 2 Tiryió, 9 Mekranoiti e 6 Xicrins. Das 44 amostras de soro oriundas de migrantes japonese...
Inhibition of feline leukemia virus replication in chronically infected cell li...
Ornelas, Sócrates Souza; Barra, Gustavo Barcelos; Kanzaki, Luis Isamu BarrosFeline Leukemia virus (FeLV) is a pathogenic retrovirus endemic among domestic cats, remaining a serious disease since its discovery in 1964. RNA interference (RNAi) is a process in which double-stranded RNA induces the post-transcriptional sequence-specific degradation of homologous messenger RNA. At present, RNAi technology is regarded as a potential strategy for the treatment of various diseases as it can be...
Human T-Lymphotropic viruses evolution possibly explained by primate deltaretro...
Kanzaki, Luis Isamu Barros; Casseb, Jorge Simão do RosárioThe primate T cell lymphotropic virus group comprises pathogenic and apathogenic agents found in human and simian hosts. Up to date, three types of the simian T cell lymphotropic virus/STLV and four types of the human T cell lymphotropic virus/HTLV have been isolated and characterized from non human primates and from human hosts respectively. We have not found evidences of STLV-1 infection among new world monke...
Antibody to human T-lymphotropic virus in a patient with Guillain-Barré syndrom...
Nakauchi, C.M.; Linhares, Alexandre da Costa; Gomes, M.L.C.; Maruyama, Koshi; Kanzaki, Luis Isamu Barros; Azevedo, Vânia NakauthAmostra de soro obtida de paciente com a síndrome de Guillain-Barré revelou-se positiva quanto à presença de anticorpos para o vírus linfotrópico humano T (HTLV-I) pelo método imuno-enzimático (ELISA) e a análise por "Western-Blot". Resultaram negativos os testes visando à detecção de enterovírus (incluindo poliovírus) a partir de material fecal, tanto em cultura de tecidos como em camundongos recém-nascidos; e...
Predictors of virologic failure in HIV/AIDS patients treated with highly active...
Bello, Edson José Monteiro; Correia, Amabel Fernandes; Marins, José Ricardo Pio; Merchán-Hamann, Edgar; Kanzaki, Luis Isamu BarrosLittle data exists concerning the efficacy of the antiretroviral therapy in the Federal District in Brazil, therefore in order to improve HIV/AIDS patients’ therapy and to pinpoint hot spots in the treatment, this research work was conducted. Of 139 HIV/AIDS patients submitted to the highly active antiretroviral therapy, 12.2% failed virologically. The significant associated factors related to unresponsiveness ...