4 documents found, page 1 of 1
METABOLIC PROFILING AND CYTOTOXIC ACTIVITY OF METHANOL EXTRACTS FROM CHAMAECRIS...
Lima,Daniele Rodrigues de; Franca,Maria Gleiziane de Araújo; Oliveira,Fátima de Cássia Evangelista de; Pessoa,Cláudia do Ó; Cavalheiro,Alberto JoséThe genus Chamaecrista comprises more than 330 species, with only a few studies on their chemical composition and biologic activities. In this study, the phytochemical profile of leaf, stems, and fruits extracts of the C. duckeana were examined by UPLC ESI HRMS analysis to determine possibly bioactive constituents. The antioxidant activity was carried out through in vitro assay, by the sequestration of the free...
Antioxidant mechanisms of iso-6-cassine in suppressing seizures induced by pilo...
Freitas,Rivelilson Mendes de; Silva,Fábio de Oliveira; Silva,Maria Goretti de Vasconcelos; Feng,DejiangThe aim of this study was to evaluate the in vitro antioxidant effects of 12-[(2R,5R,6R)-5-hydroxy-6-methylpiperidin-2-yl]dodecan-2-one (iso-6-cassine; ISO) and the anticonvulsant effects of ISO on pilocarpine-induced seizures in rats. Wistar rats were treated with 0.9% saline (i.p., control group), pilocarpine (400 mg/kg, i.p., pilocarpine group), and the association of ISO (1.0 mg/kg, i.p.) plus pilocarpine (...
Constituintes químicos das folhas de Senna spectabilis (DC) Irwin & Barneby...
Silva,Fábio de Oliveira; Oliveira,Írvila Ricarte de; Silva,Maria Goretti de Vasconcelos; Braz-Filho,RaimundoFrom leaves of Senna spectabilis var. excelsa were isolated caffeine, the triterpenes lupeol, α-amyrin, β-amyrin, cycloeucalenol, friedelin and ursolic, oleanolic and betulinic acids, besides the steroids sitosterol and stigmasterol and their respective glucosides. The structures of these compounds were established by spectroscopic analysis including two-dimensional NMR methods and comparison with published spe...
Constituintes químicos do caule de Senna reticulata Willd. (Leguminoseae): Chem...
Santos,Rogério Nunes dos; Silva,Maria Goretti de Vasconcelos; Braz Filho,RaimundoThe phytochemical investigation of the wood extracts of Senna reticulata (Leguminoseae) yielded six anthraquinones: chrysophanol, physcion, aloe-emodin, 1,3,8-trihydroxyanthraquinone, 3-methoxy-1,6,8-trihydroxyanthraquinone, emodin and the chrysophanol-10,10' bianthrone. The triterpenes a and b-amirin, the steroids b-sitosterol and stigmasterol as well as the flavonoid kaempferol were also identified. The struc...