3 documents found, page 1 of 1
Association between cardiovascular autonomic neuropathy and left ventricular hy...
Ponte, Clarisse Mourão Melo; Fernandes, Virgínia Oliveira; Liberato, Christiane Bezerra Rocha; Montenegro, Ana Paula Dias Rangel; Batista, Lívia AlineBackground: Congenital generalized lipodystrophy (CGL) is a rare disorder characterized by the absence of subcutaneous adipose tissue, severe insulin resistance, diabetes mellitus, and cardiovascular complications, including cardiac autonomic neuropathy (CAN), left ventricular hypertrophy (LVH), and atherosclerosis. The present study aimed to access the association between CAN parameters and cardiovascular abno...
Early commitment of cardiovascular autonomic modulation in Brazilian patients w...
Ponte, Clarisse Mourão Melo; Fernandes, Virgínia Oliveira; Gurgel, Maria Helane Costa; Vasconcelos, Izabella Tamira Galdino FariasBackground: Metabolic abnormalities in congenital generalized lipodystrophy (CGL) are associated with microvascular complications. However, the evaluation of different types of neuropathy in these patients, including the commitment of cardiovascular autonomic modulation, is scarce. The objective of the present study was to determine the prevalence of cardiovascular autonomic neuropathy (CAN) in patients with CG...
Homozygous and heterozygous nuclear lamin A p.R582C mutation: different lipodys...
Montenegro Jr., Renan Magalhães; Costa-Riquetto, Aline Dantas; Fernandes, Virgínia Oliveira; Montenegro, Ana Paula Dias Rangel; Santana, Lucas Santos deBackground: Dunnigan-type familial partial lipodystrophy (FPLD2) is a rare autosomal dominant disease caused by heterozygous mutations in the LMNA gene that results in regional loss of subcutaneous adipose tissue with onset in puberty. However, a generalized lipodystrophy phenotype has also been associated with heterozygous mutations in this gene, demonstrating the noticeable phenotypic heterogeneity of this di...