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The pathophysiology of rett syndrome with a focus on breathing dysfunctions

Ramirez, Jan-Marino; Karlen-Amarante, Marlusa [UNESP]; Wang, Jia-Der Ju; Bush, Nicholas E.; Carroll, Michael S.; Weese-Mayer, Debra E.; Huff, Alyssa

Made available in DSpace on 2021-06-25T10:36:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01; Rett syndrome (RTT), an X-chromosome-linked neurological disorder, is characterized by serious pathophysiology, including breathing and feeding dysfunctions, and alteration of cardiorespiratory coupling, a consequence of multiple interrelated disturbances in the genetic and homeostatic regulation of cen...

Date: 2021   |   Origin: Oasisbr

Optogenetic stimulation of Dbx1 neurons promote increas in sympathetic activity...

Karlen-Amarante, Marlusa [UNESP]; Huff, Alyssa; Baertsch, Nathan; Colombari, Debora [UNESP]; Ramirez, Jan-Marino

Made available in DSpace on 2021-06-25T11:20:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-04-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); NIH; Sao Paulo State Univ UNESP, Sch Dent, Sao Paulo, Brazil; Seattle Childrens Res Inst, Seattle, WA USA; Sao Paulo State Univ UNESP, Sch Dent, Sao Paulo, Brazil; FAPESP: 2016/23513-1; FAPESP: 2019/11969-2; NIH: P01 HL090554; NIH: R01 HL144...

Date: 2021   |   Origin: Oasisbr

Inhibitory control of active expiration by the Bötzinger complex in rats

Flor, Karine C. [UNESP]; Barnett, William H.; Karlen-Amarante, Marlusa [UNESP]; Molkov, Yaroslav I.; Zoccal, Daniel B. [UNESP]

Made available in DSpace on 2020-12-12T02:16:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Key points: Contraction of abdominal muscles at the end of expiration during metabolic challenges (such as hypercapnia and hypoxia) improves pulmonary ventilation. The emergence of this active expiratory pattern requires the recruitment of the expiratory oscillator located on the ventral surface of the ...

Date: 2020   |   Origin: Oasisbr

Renovascular hypertension elevates pulmonary ventilation in rats by carotid bod...

Melo, Mariana Rosso [UNESP]; Gasparini, Silvia [UNESP]; Silva, Elaine F. [UNESP]; Karlen-Amarante, Marlusa [UNESP]; Speretta, Guilherme F. [UNESP]

Made available in DSpace on 2020-12-12T02:38:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-02-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The two kidney-one clip (2K1C) renovascular hypertension depends on the renin-angiotensin system and sympathetic overactivity. The maintenance of 2K1C hypertension also de...

Date: 2020   |   Origin: Oasisbr

Postnatal intermittent hypoxia enhances phrenic and reduces vagal upper airway ...

Bittencourt-Silva, Paloma G. [UNESP]; Menezes, Miguel Furtado [UNESP]; Mendonça-Junior, Bolival A. [UNESP]; Karlen-Amarante, Marlusa [UNESP]

Made available in DSpace on 2020-12-12T01:46:18Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); New Findings: What is the central question of this study? What are the alterations in respiratory motor activity that may underlie ventilatory dysfunctions in juvenile and adult animals exposed to postnatal chronic intermittent hypoxi...

Date: 2020   |   Origin: Oasisbr

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