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Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in...

Bielefeld, P; Martirosyan, A; Martín-Suárez, S; Apresyan, A; Meerhoff, GF; Pestana, F; Poovathingal, S; Reijner, N; Koning, W; Clement, RA; Veen, IVd

Traumatic brain injury (TBI) can result in long-lasting changes in hippocampal function. The changes induced by TBI on the hippocampus contribute to cognitive deficits. The adult hippocampus harbors neural stem cells (NSCs) that generate neurons (neurogenesis), and astrocytes (astrogliogenesis). While deregulation of hippocampal NSCs and neurogenesis have been observed after TBI, it is not known how TBI may aff...


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