During the COVID-19 pandemic, the emergence and detection of SARS-CoV-2 variants of concern highlighted the pivotal role of genomic epidemiology in public health decision and policy making. The pandemic also revealed a need for genomic epidemiologists to effectively engage with a broader audience, including policymakers and the public. To address this need, we introduced a new transdisciplinary training worksho...
Background: Yellow fever virus remains a major public health threat in Brazil, where recent resurgence risks affecting both forest and periurban populations. Understanding viral movement across ecological settings is critical to support early detection and prevent outbreaks. Methods: We performed genomic surveillance in two Brazilian states, a northern Amazon region and a southeastern region, between 2023 and 2...
Background: Italy was significantly affected by the COVID-19 pandemic, experiencing multiple waves of infection following the sequential emergence of new variants. Understanding the transmission patterns and evolution of SARS-CoV-2 is vital for future preparedness. Methods: We conducted an analysis of viral genome sequences, integrating epidemiological and phylodynamic approaches, to characterize how SARS-CoV-2...
Background: This study focuses on urban arboviruses, specifically dengue (DENV), chikungunya (CHIKV), and Zika (ZIKV), which pose a significant public health challenge in Rio de Janeiro state, Southeast Brazil. In our research, we highlight critical findings on the transmission dynamics of these arboviruses in Rio de Janeiro, identifying distinct patterns of disease spread. Methods: By combining genomic data wi...
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Made available in DSpace on 2022-04-28T19:46:04Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01; The Lambda variants of interest (VOI) (C37/GR/452Q.V1/21G) was initially reported in Lima, Peru but has gained rapid dissemination through other Latin American countries. Nevertheless, the dissemination and molecular epidemiology of the Lambda VOI in Brazil is unknown apart from a single case report. In...
Made available in DSpace on 2022-04-28T17:21:53Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-04-01; National Institutes of Health USA; CRP-ICGEB RESEARCH GRANT 2020 Project; Oswaldo Cruz Foundation; Brazilian Ministry of Health; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ); European Union's Horizon 2020 researc...
Made available in DSpace on 2022-04-28T19:47:50Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-15; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Financiadora de Estudos e Projetos; The SARS-CoV-2 alpha VOC (also known as lineage B.1.1.7) initially described in the autumn, 2020 in UK, rapidly became the dominant lineage across much of Europe. Despite multiple studies reporting molecul...
Made available in DSpace on 2022-04-28T19:51:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-01-01; Delta VOC is highly diverse with more than 120 sublineages already described as of November 30, 2021. In this study, through active monitoring of circulating severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants in the state of São Paulo, southeast Brazil, we identified two emerging subl...
Made available in DSpace on 2022-04-29T08:46:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The current COVID-19 pandemic demands massive testing by Real-time RT-PCR (Reverse Transcription Polym...