3 documents found, page 1 of 1
Management of patients at very high risk of osteoporotic fractures through sequ...
Curtis, Elizabeth M.; Reginster, Jean-Yves; Al-Daghri, Nasser; Biver, Emmanuel; Brandi, Maria Luisa; Cavalier, Etienne; Hadji, Peyman; Halbout, PhilippeOsteoporosis care has evolved markedly over the last 50 years, such that there are now an established clinical definition, validated methods of fracture risk assessment and a range of effective pharmacological agents. Currently, bone-forming (anabolic) agents, in many countries, are used in those patients who have continued to lose bone mineral density (BMD), patients with multiple subsequent fractures or those...
Role of vitamin D supplementation in the management of musculoskeletal diseases...
Chevalley, Thierry; Brandi, Maria Luisa; Cashman, Kevin D.; Cavalier, Etienne; Harvey, Nicholas C.; Maggi, Stefania; Cooper, Cyrus; Al-Daghri, NasserVitamin D is a key component for optimal growth and for calcium-phosphate homeostasis. Skin photosynthesis is the main source of vitamin D. Limited sun exposure and insufficient dietary vitamin D supply justify vitamin D supplementation in certain age groups. In older adults, recommended doses for vitamin D supplementation vary between 200 and 2000 IU/day, to achieve a goal of circulating 25-hydroxyvitamin D (c...
Geographical variation in DXA bone mineral density in young European men and wo...
Kaptoge, Stephen; Silva, José A. da; Brixen, Kim; Reid, David M.; Kröger, Heikki; Nielsen, Torben L.; Andersen, Marianne; Hagen, Claus; Lorenc, RomanWe collected population-based young normal hip and spine BMD data from 17 centres across Europe to assess between centre differences and to compare reference values with the US NHANES-III data. There was strong evidence of between country heterogeneity, but not between centres within countries. Hip BMD mean values were lower in European women, but SD's differed little from the NHANES-III USA results in both sex...