2 documents found, page 1 of 1
A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angi...
Ong, Yu Ting; Andrade, Jorge; Armbruster, Max; Shi, Chenyue; Castro, Marco; Costa, Ana S. H.; Sugino, Toshiya; Eelen, Guy; Zimmermann, BarbaraFunding Information: The research in the M.P. laboratory was supported by the Max Planck Society, the European Research Council (ERC) Consolidator Grant EMERGE (no. 773047), the Deutsche Forschungsgemeinschaft (DFG, Project-ID 75732319 – SFB 834), the Leducq Foundation, the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie action (no. 814316), the Excellence Cluste...
Control of endothelial quiescence by FOXO-regulated metabolites
Andrade, Jorge; Shi, Chenyue; Costa, Ana S. H.; Choi, Jeongwoon; Kim, Jaeryung; Doddaballapur, Anuradha; Sugino, Toshiya; Ong, Yu Ting; Castro, Marco(DFG, German Research Foundation) -Project-ID 75732319 -SFB 834, EXC 2026, project ID 390649896) DFG -Project-ID 268555672 -SFB 1213 MRC_MC_UU_12022/6 Cancer Center Support Grant 5P30CA045508; Endothelial cells (ECs) adapt their metabolism to enable the growth of new blood vessels, but little is known how ECs regulate metabolism to adopt a quiescent state. Here, we show that the metabolite S-2-hydroxyglutarate ...