The combined action of waves, surges and tides can cause flooding, erosion and dune and structure overtopping in many coastal regions. Addressing emergency and risk management in these areas require a combination of targeted campaigns and real-time data that measure all phenomena at stake and can be used to develop comprehensive monitoring platforms. These monitoring platforms can support the development of pre...
The combined action of waves, surges and tides can cause flooding, erosion and dune and structure overtopping in many coastal regions. Addressing emergency and risk management in these areas require a combination of targeted campaigns and real-time data that measure all phenomena at stake and can be used to develop comprehensive monitoring platforms. These monitoring platforms can support the development of pre...
Background: Needle-exchange programs (NEPs) reduce infections in people who inject drugs. This study assesses the impact community pharmacies have had in the Needle-Exchange Program in Portugal since 2015. Methods: Health gains were measured by the number of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections averted, which were estimated, in each scenario, based on a standard model in the...
Introduction: Denosumab reduces the risk of osteoporosis fractures in post-menopausal women. Its cost and its added therapeutic value vs. zoledronic acid justify performing an economic evaluation in the Portuguese context. A societal perspective was adopted. Methods: A Markov model simulated the risk of osteoporosis fractures (hip, vertebrae, wrist and others) across patients’ lifetime, considering their clinic...
Wireless Sensor Networks (WSN) are being progressively used in several application areas, particularly to collect data and monitor physical processes. Moreover, sensor nodes used in environmental monitoring applications, such as the aquatic sensor networks, are often subject to harsh environmental conditions while monitoring complex phenomena. Non-functional requirements, like reliability, security or availabil...
The burden of pneumococcal disease in adults is substantial from a social and economic point of view. This study assessed the cost-effectiveness of the 13-valent pneumococcal conjugate vaccine (PCV13) for the prevention of invasive pneumococcal disease and pneumococcal pneumonia in adults versus "no vaccination" and versus vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPSV23). A Markov mod...
Background : Pneumococcal infections are the leading cause of vaccinepreventable death in children. In June 2015, the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in the Portuguese Immunization Program. We evaluated the cost-effectiveness of children vaccinated with PCV13 versus no vaccination for preventing pneumococcal diseases. Methods: A cohort simulation model for 2014 Portuguese newborn...
Background: Needle and syringe programmes (NSP) are a critical component of harm reduction interventions among people who inject drugs (PWID). Our primary objective was to summarize the evidence on the effectiveness of NSP for PWID in reducing blood-borne infection transmission and injecting risk behaviours (IRB). Methods: We conducted an overview of systematic reviews that included PWID (excluding prisons and ...