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Transthyretin Proteins Regulate Angiogenesis by Conferring Different Molecular ...
Nunes, R. J.; de Oliveira, P.; Lages, A.; Becker, J. D.; Marcelino, P.; Barroso, E.; Perdigoto, R.; Kelly, J. W.; Quintas, A.; Santos, S. C. R.Familial amyloidotic polyneuropathy (FAP) has a high prevalence in Portugal, and the most common form of hereditary amyloidosis is caused by an amyloidogenic variant of transthyretin (TTR) with a substitution of methionine for valine at position 30 (V30M). Until now, the available efficient therapy is liver transplantation, when performed in an early phase of the onset of the disease symptoms. However, transpla...
Date: 2013
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Origin: ARCA - Access to Research and Communication Annals