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Curcumins and its derivatives as potential inhibitors of New Coronavirus (COVID...

Alves, Daniela Ribeiro; Rocha, Matheus Nunes da; Passos, Camila Caldas Oliveira; Marinho, Márcia Machado; Marinho, Emmanuel Silva

Coronavirus (COVID-19) disease outbreak caused a worldwide pandemic with a powerful lethal potential and still, there is no specific treatment to it. Natural bioactive molecules like curcumins were investigated in this work aiming to block the active site of COVID-19 Main protease (Mpro), since they present several biological activities, being more suitable in terms of fewer side effects, once this disease over...

Date: 2022   |   Origin: Oasisbr

Knowing Robotox: A profile of monitoring and releasing pesticides in Brazil

Sousa, Damião Sampaio de; Mendes, Francisco Rogênio da Silva; Marinho, Márcia Machado; Lima, Glória Fernandes; Santos, Hélcio Silva dos

Pesticides are products intended for the production sector, whose purpose is to preserve ecosystems by altering the composition of flora or fauna in order to preserve them from the harmful action of living beings considered harmful. The insertion of pesticides in Brazil is due to the Green Revolution, the mechanization and the intense use of agricultural inputs. As a result, damage to workers' health and the en...

Date: 2022   |   Origin: Oasisbr

Teacher education in the student perspective:

Vasconcelos, Sandro Olímpio Silva; Marinho, Márcia Machado; Marinho, Emmanuel Silva; Medeiros, Normândia de Farias Mesquita

Experience is an essential element for meaningful learning, although teacher formation does not always pay due attention to the elements that underlie this human aspect. The study presented in this text analyzes the discourses of the 20 students of the Degree in Biological Sciences who completed the discipline Fundamentals of Philosophy of Sciences at the State University of Ceará, UECE, Iguatu campus, in the y...

Date: 2020   |   Origin: Oasisbr

Molecular fractionation with conjugate caps study of the interaction of the ana...

Marinho, Márcia Machado; Santos, Ricardo Pires dos; Bezerra, Eveline Matias; Costa, Roner Ferreira; Figueira, Ciro Siqueira; Martins, Alice Maria Costa

Objective: The objective of this study was to use the molecular fractionation with conjugate caps (MFCC) method to elucidate the possible interaction mechanism of anacardic acid (AA) with the saturated alkyl chain (AA0) in the Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase (TcGAPHD) enzyme. Methods: Initially, the geometry optimization of the AA three-dimensional structure (with the pentadecyl chain...

Date: 2020   |   Origin: Oasisbr

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