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Placental microphysiological systems: new advances on promising platforms that ...

Gonçalves, Inês M.; Afzal, Muhammad; Kennedy, Nithil; Moita, Ana; Lima, Rui Alberto Madeira Macedo; Ostrovidov, Serge; Hori, Takeshi; Nashimoto, Yuji

One of the most complex human physiological processes to study is pregnancy. Standard animal models, as well as two-dimensional models, lack the complexity and biological relevance required to accurately study such a physiological process. Recent studies have focused on the development of three-dimensional models based on microfluidic systems, designated as placental microphysiological systems (PMPSs). PMPS dev...


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