2 documents found, page 1 of 1
Towards a consensus definition of allostatic load: a multi-cohort, multi-system...
McCrory, C; McLoughlin, S; Layte, R; NiCheallaigh, C; O'Halloran, AM; Barros, H; Berkman, LF; Bochud, M; Crimmins, EM; Farrell, MT; Fraga, S; Grundy, EBackground: Allostatic load (AL) is a multi-system composite index for quantifying physiological dysregulation caused by life course stressors. For over 30 years, an extensive body of research has drawn on the AL framework but has been hampered by the lack of a consistent definition.Methods: This study analyses data for 67,126 individuals aged 40-111 years participating in 13 different cohort studies and 40 bio...
Socioeconomic status, non-communicable disease risk factors, and walking speed ...
Stringhini, S; Carmeli, C; Jokela, M; Avendaño, M; McCrory, C; d'Errico, A; Bochud, M; Barros, H; Costa, G; Chadeau-Hyam, M; Delpierre, C; Gandini, MObjective To assess the association of low socioeconomic status and risk factors for non-communicable diseases (diabetes, high alcohol intake, high blood pressure, obesity, physical inactivity, smoking) with loss of physical functioning at older ages. Design Multi-cohort population based study. Setting 37 cohort studies from 24 countries in Europe, the United States, Latin America, Africa, and Asia, 1990-2017 P...