6 documents found, page 1 of 1
Pre-existing IgG antibodies to HCoVs NL63 and OC43 spike increased during the p...
Hasan, Zahra; Masood, Kiran Iqbal; Veldhoen, Marc; Qaiser, Shama; Alenquer, Marta; Akhtar, Mishgan; Balouch, Sadaf; Iqbal, Junaid; Wassan, YaqubPreexisting immunity may be associated with increased protection against non-related pathogens such as, SARS-CoV-2. There is little information regarding endemic human coronaviruses (HCOVs) from Pakistan, which experienced a relatively low COVID-19 morbidity and mortality. We investigated antibodies to SARS-CoV-2 and HCoVs NL63 and OC43, comparing sera from prepandemic controls (PPC) period with responses in he...
Correction: IgG antibodies to SARS-CoV-2 in asymptomatic blood donors at two ti...
Hasan, Muhammad; Moiz, Bushra; Qaiser, Shama; Masood, Kiran Iqbal; Ghous, Zara; Hussain, Areeba; Ali, Natasha; Simas, J. Pedro; Veldhoen, Marc
Humoral and T cell responses to SARS-CoV-2 reveal insights into immunity during...
Masood, Kiran Iqbal; Qaiser, Shama; Abidi, Syed Hani; Khan, Erum; Mahmood, Syed Faisal; Hussain, Areeba; Ghous, Zara; Imtiaz, Khekahsan; Ali, NatashaBackground: Protection against SARS-CoV-2 is mediated by humoral and T cell responses. Pakistan faced relatively low morbidity and mortality from COVID-19 through the pandemic. To examine the role of prior immunity in the population, we studied IgG antibody response levels, virus neutralizing activity and T cell reactivity to Spike protein in a healthy control group (HG) as compared with COVID-19 cases and indi...
Investigating the impact of prior COVID-19 on IgG antibody and interferon γ res...
Hasan, Zahra; Masood, Kiran Iqbal; Qaiser, Shama; Khan, Erum; Hussain, Areeba; Ghous, Zara; Khan, Unab; Yameen, Maliha; Hassan, ImranBackground and Aims: COVID-19 vaccinations have reduced morbidity and mortality from the disease. Antibodies against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) have been associated with immune protection. Seroprevalence studies revealed high immunoglobulin G (IgG) antibody levels to SARS-CoV-2 in the Pakistani population before vaccinations. We investigated the effect of BBIBP-CorV vaccination...
A rapid real-time polymerase chain reaction-based live virus microneutralizatio...
Abidi, Syed Hani; Imtiaz, Kehkashan; Kanji, Akbar; Qaiser, Shama; Khan, Erum; Iqbal, Kiran; Veldhoen, Marc; Ghias, Kulsoom; Simas, J. PedroBackground Individuals recovering from COVID-19 are known to have antibodies against the Spike and other structural proteins. Antibodies against Spike have been shown to display viral neutralization. However, not all antibodies against Spike have neutralizing ability although they may be cross-reactive. There is a need for easy-to-use SARS-CoV-2 neutralizing assays for the determination of virus-neutralizing ac...
A rapid real-time polymerase chain reaction-based live virus microneutralizatio...
Abidi, Syed Hani; Imtiaz, Kehkashan; Kanji, Akbar; Qaiser, Shama; Khan, Erum; Iqbal, Kiran; Veldhoen, Marc; Ghias, Kulsoom; Simas, J Pedro; Hasan, ZahraBackground: Individuals recovering from COVID-19 are known to have antibodies against the Spike and other structural proteins. Antibodies against Spike have been shown to display viral neutralization. However, not all antibodies against Spike have neutralizing ability although they may be cross-reactive. There is a need for easy-to-use SARS-CoV-2 neutralizing assays for the determination of virus-neutralizing a...