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ERN ReCONNET points to consider for treating patients living with autoimmune rh...
Talarico, Rosaria; Ramirez, Giuseppe Alvise; Barreira, Sofia; Cardamone, Chiara; Triggianese, Paola; Aguilera, Silvia; Andersen, Jeanette; Avcin, TadejRecent studies have shown that people who are immunocompromised may inadvertently play a role in spurring the mutations of the virus that create new variants. This is because some immunocompromised individuals remain at risk of getting COVID-19 despite vaccination, experience more severe disease, are susceptible to being chronically infected and remain contagious for longer if they become infected and consideri...
Anxiety and depression in patients with giant cell arteritis
Martinho, Joana Martins; Ponte, André; Dourado, Eduardo; Khmelinskii, Nikita; Barreira, Sofia C.; Machado, Ana R. Cruz; Macieira, Carla; Teixeira, VítorObjectives To compare the prevalence of anxiety and depression in patients with GCA with that in the general population, using the Hospital Anxiety and Depression Scale (HADS), and to identify independent predictors of these psychiatric manifestations in patients with GCA.Methods We conducted a cross-sectional study including all patients diagnosed with GCA followed during 1 year in a vasculitis outpatient clin...
Efficacy of intravenous immunoglobulin in shrinking lung syndrome associated wi...
António, Manuel; Khmelinskii, Nikita; Fonseca, João EuricoShrinking lung syndrome is a rare manifestation of connective tissue diseases, namely systemic lupus erythematosus. It is characterised by reduced lung volumes and extra-pulmonary restrictive ventilatory pattern with good response to high-dose glucocorticoids alone or in combination with a second immunosuppressive agent. Here, we describe a case associated with mixed connective tissue disease and effectively tr...
SARS-CoV-2 outbreak in immune-mediated inflammatory diseases: the Euro-COVIMID ...
Saadoun, David; Vieira, Matheus; Vautier, Mathieu; Baraliakos, Xenofon; Andreica, Ioana; Silva, José A. P. da; Sousa, Marlene; Luís, MarianaBackground The COVID-19 pandemic has raised numerous questions among patients with immune-mediated inflammatory diseases regarding potential reciprocal effects of COVID-19 and their underlying disease, and potential effects of immunomodulatory therapy on outcomes related to COVID-19. The seroprevalence of SARS-CoV-2 and factors associated with symptomatic COVID-19 in patients with immune-mediated inflammatory d...
Localized forms of Vasculitis
Martins Martinho, Joana; Dourado, Eduardo; Khmelinskii, Nikita; Espinosa, Pablo; Ponte, CristinaPurpose of review: To provide an updated review on epidemiology, clinical manifestations, diagnostic assessment, treatment, and prognosis of localized vasculitis, following the 2012 Revised International Chapel Hill Consensus Conference Nomenclature on single-organ vasculitis. Recent findings: Localized, single-organ vasculitides encompass a group of rare conditions in which there is no evidence of concomitant ...
Gastric adenocarcinoma presenting as a rheumatoid factor and anti-cyclic citrul...
Silvério-António, Manuel; Parlato, Federica; Martins, Patrícia; Khmelinskii, Nikita; Braz, Sandra; Fonseca, João Eurico; Polido Pereira, JoaquimA 64-year-old male presented with a 6-month history of symmetric polyarthritis involving proximal interphalangeal joints and metacarpophalangeal joints of the hands, wrists, and ankles. Associated symptoms included vomiting, progressive fatigue, and weight loss. Laboratory results showed microcytic anemia, leukocytosis, thrombocytosis, elevated C-reactive protein and erythrocyte sedimentation rate, and rheumato...
Ultrasound halo sign as a potential monitoring tool for patients with giant cel...
Ponte, Cristina; Monti, Sara; Scirè, Carlo Alberto; Delvino, Paolo; Khmelinskii, Nikita; Milanesi, Alessandra; Teixeira, Vítor; Brandolino, FabioObjectives: To assess the sensitivity to change of ultrasound halo features and their association with disease activity and glucocorticoid (GC) treatment in patients with newly diagnosed giant cell arteritis (GCA). Methods: Prospective study of patients with ultrasound-confirmed GCA who underwent serial ultrasound assessments of the temporal artery (TA) and axillary artery (AX) at fixed time points. The number ...
SARS-CoV-2 outbreak in immune-mediated inflammatory diseases : the Euro-COVIMID...
Saadoun, David; Vieira, Matheus; Vautier, Mathieu; Baraliakos, Xenofon; Andreica, Ioana; da Silva, José A. P.; Sousa, Marlene; Luis, MarianaBackground: The COVID-19 pandemic has raised numerous questions among patients with immune-mediated inflammatory diseases regarding potential reciprocal effects of COVID-19 and their underlying disease, and potential effects of immunomodulatory therapy on outcomes related to COVID-19. The seroprevalence of SARS-CoV-2 and factors associated with symptomatic COVID-19 in patients with immune-mediated inflammatory ...
A non-infectious uveitis multidisciplinary clinic in a tertiary referral center...
Leal, Ines; Romão, Vasco C.; Sousa Mano, Sofia; Khmelinskii, Nikita; Campanilho-Marques, Raquel; Ponte, Cristina; Macieira, CarlaNon-infectious uveitis (NIU) is a group of sight-threatening diseases that generates significant burden for the healthcare systems due to its adverse outcomes, irreversible structural complications in the eye with loss of visual function, limited clinical expertise and low-grade evidence for best practice. The usefulness of multidisciplinary care, specifically close collaboration between Rheumatologists and Oph...
Reuma.pt/vasculitis : the Portuguese vasculitis registry
Ponte, Cristina; Khmelinskii, Nikita; Teixeira, Vítor; Luz, Karine; Peixoto, Daniela; Rodrigues, Marília; Luís, Mariana; Teixeira, Lídia; Sousa, SandraBackground: The vasculitides are a group of rare diseases with different manifestations and outcomes. New therapeutic options have led to the need for long-term registries. The Rheumatic Diseases Portuguese Register, Reuma.pt, is a web-based electronic clinical record, created in 2008, which currently includes specific modules for 12 diseases and > 20,000 patients registered from 79 rheumatology centres. On Oct...