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Occupational exposure to Cr(VI) in Finland in 1980–2016 and related lung cancer...

Mahiout, Selma; Kiilunen, Mirja; Vermeire, Theo; Viegas, Susana; Woutersen, Marjolijn; Santonen, Tiina

Occupational exposure to hexavalent chromium [Cr(VI)], a known lung carcinogen, remains a relevant concern. When performing exposure assessment for risk assessment, biomonitoring is an important tool, reflecting actual internal exposure of workers. Here, we present total urinary chromium (U-Cr) biomonitoring data from several occupational sectors, spanning 1980-2016 (n > 42,000). Based on this data, we estimate...


Setting up a collaborative European human biological monitoring study on occupa...

Santonen, Tiina; Alimonti, Alessandro; Bocca, Beatrice; Duca, Radu Corneliu; Galea, Karen S.; Godderis, Lode; Göen, Thomas; Gomes, Bruno; Hanser, Ogier

The EU human biomonitoring initiative, HBM4EU, aims to coordinate and advance human biomonitoring (HBM) across Europe. Within its remit, the project is gathering new, policy-relevant, EU-wide data on occupational exposure to relevant priority chemicals and developing new approaches for occupational biomonitoring. In this manuscript, the hexavalent chromium (Cr(VI)) study design is presented as the first example...


Setting up a collaborative European human biological monitoring study on occupa...

Santonen, Tiina; Alimonti, Alessandro; Bocca, Beatrice; Duca, Radu Corneliu; Galea, Karen S; Godderis, Lode; Göen, Thomas; Gomes, Bruno; Hanser, Ogier

The EU human biomonitoring initiative, HBM4EU, aims to co-ordinate and advance human biomonitoring (HBM) across Europe. Within its remit, the project is gathering new, policy relevant, EU-wide data on occupational exposure to relevant priority chemicals and developing new approaches for occupational biomonitoring. In this manuscript, the hexavalent chromium [Cr(VI)] study design is presented as the first exampl...


Setting up a collaborative European Human biological monitoring study on occupa...

Santonen, Tiina; Alimonti, Alessandro; Bocca, Beatrice; Duca, Radu Corneliu; Galea, Karen S.; Godderis, Lode; Göen, Thomas; Gomes, Bruno; Hanser, Ogier

Background: The EU human biomonitoring initiative, HBM4EU, aims to co-ordinate and advance human biomonitoring across Europe and develop new approaches for biomonitoring. Hexavalent chromium (Cr(VI)) is an important occupational carcinogen, which compounds are currently authorized in Europe. In addition, a binding limit value for occupational exposure to Cr(VI) has been recently agreed in EU. These regulatory a...


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