2 documents found, page 1 of 1
Ternatin pretreatment attenuates testicular injury induced by torsion/detorsion...
Guimarães,Sergio Botelho; Santos,Jefferson Menezes Viana; Aragão,Alan Arruda; Kimura,Osamu Sandes; Silveira,Edilberto RPURPOSE: To investigate the possible protective role of the bioflavonoid ternatin (TTN) when administered before induction of ischemia/reperfusion injury in rat testis. METHODS: Thirty-six Wistar rats were randomly assigned to 3 groups (n=12), divided in 2 subgroups (n=6). Saline 2.0ml (G-1), dimethylsulfoxide (DMSO) 3% solution (G-2) or TTN 12 mg/kg/dose (G-3) was administered ip. to all rats, respectively, 21...
Dimethylsulfoxide attenuates ischemia-reperfusion injury in rat testis
Guimarães,Sergio Botelho; Kimura,Osamu Sandes; Vasconcelos,Paulo Roberto Leitão dePURPOSE: To evaluate the protective role of dimethylsulfoxide (DMSO) in a rat model of testis ischemia/reperfusion (I/R). METHODS: Twenty-four male Wistar rats were randomized in two equal groups. Control rats (G-1) received saline 2.0 ml intraperitoneally (ip) 21, 9 and 1 h before torsion. Experimental rats (G-2) received ip injections of 3% aqueous solution of DMSO, 0.1ml/10g body weight. Saline was added to ...