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A linkage study between the GABAA beta2 and GABAA gamma2 subunit genes and majo...
Ambrósio, Alda M.; Kennedy, James L.; Macciardi, Fabio; King, Nicole; Azevedo, Maria H.; Oliveira, Catarina R.; Pato, Carlos N.Background: Alterations of the γ-aminobutyric acid (GABA) system have been implicated in the pathophysiology of major psychoses. Objective: Restriction fragment length polymorphisms associated with the human γ-aminobutyric acid type A (GABAA) β2 and GABAA γ2 subunit genes on chromosome 5q32-q35 were tested to determine whether they confer susceptibility to major psychoses. Methods: Thirty-two schizophrenic fami...
Date: 2005
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Origin: Estudo Geral - Universidade de Coimbra