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Genotypic variability and antifungal susceptibility of Candida spp. isolated fr...

Sakita, K. M.; Faria, D. R.; Tobaldini, F. K.; Bettega, E. M. S.; Negri, M.; Kioshima, E. S.; Svidzinski, T. I. E.; Bonfim-Mendonça, P. S.

Objectives Candida spp. are responsible for 9095% of hematogenous fungal infections. In Brazil and Latin America, C. albicans is the most common specie, followed by C. parapsilosis and C. tropicalis. Infections caused by Candida spp. may have their origin in exogenous sources, transmitted to patients via contaminated infusions, biomedical devices or even by the hands of the hospital staff members. Molecular bio...


Assessment of in vitro biofilm formation and antifungal susceptibility of Candi...

Faria, D. R.; Sakita, K. M.; Tobaldini, F. K.; Akimoto-Gunther, L.; Negri, M.; Kioshima, E. S.; Svidzinski, T. I. E.; Bonfim-Mendonça, P. S.

Objectives Vulvovaginal candidiasis (VVC) is an inflammation of the genital mucosa, which mainly affects the vulva and vagina. Candida spp. are considered commensal fungus, however, when there is imbalance in the microbiota or the host immune system is compromised, these can become pathogenic. C. albicans is responsible for most cases of VVC and is able of expressing mechanisms which allow the colonization or i...


Influence of Laminarin in colonisation process of Candida albicans

Bonfim-Mendonça, P. S.; Tobaldini, F. K.; Batalini, I. M.; Capoci, I. R. G.; Godoy, J. S. R.; Kioshima, E. S.; Negri, M.; Svidzinski, T. I. E.

Objective Candida albicans is responsible for the majority of cases of vulvovaginal candidiasis (VVC), one of the most important candidal virulence factors is the ability to adhere to host surfaces. Chemotherapies that seek to improve the host immune response are an alterna- tive to control fungal infections. b-glucans are polymeric carbohydrates that have been reported to modulate human inflammatory responses ...


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