83 documents found, page 1 of 9
Monoolein/phytantriol-enriched lipid-based nanocarriers loaded with resveratrol...
Faria, Maria João Fernandes; Romaguera, Maria; Gonçalves, Hugo Manuel Castro; Ribeiro, Artur; Ribeiro, Clarisse Marta Oliveira; Lira, MadalenaMost topical ophthalmic solutions to treat posterior eye disorders demonstrate low therapeutic bioavailability. This results in poor medical outcomes and underlines the need for innovative non-invasive approaches. In this study, lipid-based nanocarriers (LN) of dioctadecyldimethylammonium bromide (DODAB) enriched with monoolein (MO@LN) or phytantriol (PHY@LN) were loaded with resveratrol (RSV-MO@LN/-PHY@LN) and...
Lignin-based nanoparticles loaded with essential oils: potential for diabetic f...
Domingues, Joana Margarida Dias; Noro, Jennifer Martins; Novoa-Carballal, Ramón; Ribeiro, Artur; Monteiro, R.; Silva, C.; Felgueiras, Helena PradoEssential oils (EOs) play a pivotal role in wound healing as sustainable bioactive agents capable of counteracting infections and enhancing wound healing. Nevertheless, their application remains limited by challenges such as high volatility, photothermal resistance, and a tendency toward oxidative degradation. Encapsulation of EOs offers a promising strategy to overcome these issues by enhancing their chemical ...
Odorant-binding protein as active ingredient for fragrance release regulated by...
Gonçalves, Filipa Daniela Gomes; Tinoco, Ana; Guimarães, Diana; Silva, Carla Alexandra Pereira; Ribeiro, Artur; Cavaco-Paulo, ArturMammalian odorant-binding proteins (OBPs) represent a fascinating class of small, soluble proteins that transport odors from the air to the olfactory receptors, through the nasal mucus. OBPs can accommodate diverse odorant molecules through their flexible binding pockets, undergoing conformational changes upon ligand binding. Acknowledge of release mechanism could be very useful to provide a controllable releas...
Interaction of polypeptides with hair in different reducing environments
Carvalho, José Pedro; Costa, André Dias; Gonçalves, Filipa Daniela Gomes; Costa, André da; Ribeiro, Artur; Martins, Madalena; Tinoco, AnaInnovation in product development and cosmetic treatments is essential to meet the demands of the hair care industry. This work studied the influence of reducing environments in the interaction of polypeptides (KP peptide, ELP-KP and BSK recombinant proteins and hydrolyzed keratin) with damaged hair, to recover the hair damage. The reducing conditions resulted from thioglycolic acid and thioanisole addition. Th...
Sustainable dyeing and functionalization of knitted cotton fabrics with algae e...
Oliveira, Helena S.; Santos, Joana; Ferreira, Tânia; Ribeiro, Artur; Silva, C.; Antunes, Joana C.; Bessa, João; Oliveira, Luís Miguel; Fangueiro, RaúlAlgae extracts have emerged as a sustainable and eco-friendly alternative to synthetic dyes and functional additives in the textile industry, particularly for dyeing and functionalizing of cotton fabrics. Herein, two types of water-soluble algae extracts from Arthrospira platensis and Porphyridium cruentum were characterized in terms of thermal, structural, and functional properties and used as dye and/or funct...
Exploring bio-based alternatives to cyclopentasiloxane: paving the way to promi...
Castro, Mariana; Roque, Catarina; Loureiro, Ana Isabel Sá; Guimarães, Diana Isabel Pereira; Silva, C.; Ribeiro, Artur; Cavaco-Paulo, ArturIn recent years, significant efforts have been made to identify suitable alternatives for silicones commonly used in daily cosmetic products. However, green alternatives have faced challenges in replicating the unique properties of silicone-based formulations, particularly cyclopentasiloxane, which continues to be widely used.This study explores the potential of six biosynthesized esters (heptyl heptanoate, hep...
Tunning antisolvent precipitation for the synthesis of lignin nanoparticles usi...
Mesquita, Ricardo Marchezan Farias de; Schneider, Willian Daniel Hahn; Longo, Vinicius; Baudel, Henrique Macedo; Diebold, Eduardo; Rencoret, JorgeLignin nanoparticles (LNPs) show great potential in UV-protectants, drugs carriers, encapsulation, supercapacitors, and others. This study proposes the development of an optimised LNP synthesis method by antisolvent precipitation, using lignin from persimmon tree pruning waste, green coconut waste, and sugarcane bagasse. The best synthesis conditions were determined evaluating the chemical composition and the p...
Pioneering wound care solutions: triaxial wet-spun fibers with bioactive agents...
Miranda, Catarina Alexandra Fortuna Santos; Silva, Ana Francisca Gomes da; Evenou, Camille; Lamartine, Jérôme; Fromy, BerengereThe incidence of bacterial infections associated with chronic wounds (CWs) has increased in recent years. Thus, a triaxial wet-spun fibrous system (containing three layers) was produced for CW healing. The triaxial fibers were loaded with cinnamon leaf oil (CLO), endowed with high antibacterial, antioxidant and anti-inflammatory features, and an antimicrobial peptide alaninealanineprolinevaline (AAPV) capable o...
Lyocell/silver knitted fabrics for prospective diabetic foot ulcers treatment: ...
Tavares, Tânia Daniela Eugénio; Ribeiro, Artur; Bengoechea, Carlos; Rocha, Diana; Alcudia, Ana; Begines, Belén; Silva, C.; Antunes, Joana Isabel CostaDiabetic foot ulcers (DFUs) are a serious complication of diabetes, often resulting in infections and further health deterioration. Thus, the development of an approach combining different therapies in just one formulation to treat DFUs remains very challenging. Silver-plated polyamide fibers offer antimicrobial properties, while lyocell provides biodegradability, biocompatibility and moisture management abilit...
Biosynthesis of new amphiphilic esters with emulsifying properties for long-ter...
Roque, Catarina; Castro, Mariana; Castro, Tarsila Gabriel; Ribeiro, Artur; Silva, C.; Cavaco-Paulo, Artur; Noro, Jennifer MartinsIn this work, several amphiphilic compounds were successfully synthesized via lipase-catalysis: 2-(2-ethoxyethoxy)ethyloctanoate, 2-(2-ethoxyethoxy)ethyldecanoate, 2-(2-ethoxyethoxy)ethylpalmitate, (2-(2-ethoxyethoxy)ethyloleate) and (2-(2-ethoxyethoxy)ethyllinoleate). The reactions were carried out using octanoic acid, decanoic acid, palmitic acid, oleic acid, and linoleic acid, as the aliphatic compounds, and...