4 documents found, page 1 of 1
Clinical validation of an in-house quantitative real time PCR assay for cytomeg...
Caurio,Cassia F.B.; Allende,Odelta S.; Kist,Roger; Santos,Kênya L.; Vasconcellos,Izadora C.S.; Rozales,Franciéli P.; Lana,Daiane F. DallaAbstract Introduction: Cytomegalovirus (CMV) is one of the most common agents of infection in solid organ transplant patients, with significant morbidity and mortality. Objective: This study aimed to establish a threshold for initiation of preemptive treatment. In addition, the study compared the performance of antigenemia with qPCR results. Study design: This was a prospective cohort study conducted in 2017 in...
Urine microscopy as a biomarker of Acute Kidney Injury following cardiac surger...
Goldani,João Carlos; Poloni,José Antônio; Klaus,Fabiano; Kist,Roger; Pacheco,Larissa Sgaria; Keitel,ElizeteAbstract Introduction: Acute kidney injury (AKI) occurs in about 22% of the patients undergoing cardiac surgery and 2.3% requires renal replacement therapy (RRT). The current diagnostic criteria for AKI by increased serum creatinine levels have limitations and new biomarkers are being tested. Urine sediment may be considered a biomarker and it can help to differentiate pre-renal (functional) from renal (intrins...
Usefulness of Kidney Donor Profile Index (KDPI) to predict graft survival in a ...
Prado,Natália Petter; Silva,Cynthia Keitel da; Meinerz,Gisele; Kist,Roger; Garcia,Valter Duro; Keitel,ElizeteAbstract Introduction: Kidney Donor Profile Index (KDPI) has been incorporated in the United States to improve the kidney transplant allocation system. Objectives: To evaluate deceased kidney donors’ profile using KDPI and compare to the previous United Network for Organ Sharing (UNOS) definition of expanded criteria donors (ECD) and assess the KDPI applicability to predict five-year graft survival and renal fu...
Cost minimization analysis of an in-house molecular test for cytomegalovirus in...
Caurio,Cássia F.B.; Allende,Odelta S.; Kist,Roger; Vasconcellos,Izadora C.S.; Rozales,Francieli P.; Reck-Kortmann,Maikel; Dalla Lana,Daiane F.ABSTRACT Introduction: Cytomegalovirus may cause severe disease in immunocompromised patients. Nowadays, quantitative polymerase chain reaction is the gold-standard for both diagnosis and monitoring of cytomegalovirus infection. Most of these assays use cytomegalovirus automated molecular kits which are expensive and therefore not an option for small laboratories, particularly in the developing world. Objective...