13 documents found, page 1 of 2
Retinal OCT speckle as a biomarker for glaucoma diagnosis and staging
Vaz, Pedro G.; Brea, Luisa Sanchez; Silva, Vânia Bastos; van Eijgen, Jan; Stalmans, Ingeborg; Cardoso, João; van Walsum, Theo; Klein, StefanThis paper presents a novel image analysis strategy that increases the potential of macular Optical Coherence Tomography (OCT) by using speckle features as biomarkers in different stages of glaucoma. A large pool of features (480) were computed for a subset of macular OCT volumes of the Leuven eye study cohort. The dataset contained 258 subjects that were divided into four groups based on their glaucoma severit...
Signal-carrying speckle in optical coherence tomography: a methodological revie...
Silva, Vânia B.; Jesus, Danilo Andrade de; Klein, Stefan; van Walsum, Theo; Cardoso, João M.; Brea, Luisa Sánchez; Vaz, Pedro G.Significance: Speckle has historically been considered a source of noise in coherent light imaging. However, a number of works in optical coherence tomography (OCT) imaging have shown that speckle patterns may contain relevant information regarding subresolution and structural properties of the tissues from which it is originated. Aim: The objective of this work is to provide a comprehensive overview of the met...
A data-driven disease progression model of fluid biomarkers in genetic frontote...
van der Ende, Emma L.; Bron, Esther E.; Poos, Jackie M.; Jiskoot, Lize C.; Panman, Jessica L.; Papma, Janne M.; Meeter, Lieke H.; Dopper, Elise G. P.Several CSF and blood biomarkers for genetic frontotemporal dementia have been proposed, including those reflecting neuroaxonal loss (neurofilament light chain and phosphorylated neurofilament heavy chain), synapse dysfunction [neuronal pentraxin 2 (NPTX2)], astrogliosis (glial fibrillary acidic protein) and complement activation (C1q, C3b). Determining the sequence in which biomarkers become abnormal over the ...
Optical Coherence Tomography Imaging of the Lamina Cribrosa: Structural Biomark...
Paulo, Alice; Vaz, Pedro G.; Andrade De Jesus, Danilo; Sánchez Brea, Luisa; Van Eijgen, Jan; Cardoso, João; van Walsum, Theo; Klein, StefanThe lamina cribrosa (LC) is an active structure that responds to the strain by changing its morphology. Abnormal changes in LC morphology are usually associated with, and indicative of, certain pathologies such as glaucoma, intraocular hypertension, and myopia. Recent developments in optical coherence tomography (OCT) have enabled detailed in vivo studies about the architectural characteristics of the LC. Struc...
Escolas e a imaginação sociológica em tempos de pandemia
Paes, Amanda Gomes; Nogueira, Carolina Silva; Palau, Cecília Aguiar Silva; Batista, Chirley Mikeline Torres; Maia, Daniel Machado dos SantosEste projeto originou-se da ação de extensão Ciências Sociais nas Escolas e ancora-se em referênciaS clássicas e contemporâneas da teoria sociológica. Os objetivos se orientam pela capacidade reflexiva das ciências sociais de lidar com a diversidade da população jovem em idade escolar. Voltada tanto a professoras/es quanto a estudantes do ensino médio, a pesquisa visa aprofundar o conhecimento acerca do context...
Unfettered capitalism: on rackets, cronies and mafiosi
Klein, Stefan; Pagliuso Regatieri, RicardoIn the early 1940s, critical theory borrowed the term racket from the urban crime underworld and applied it to criticize monopoly capitalism, which was regarded as a constellation ruled in a mafia-like manner. Decades later, after the experiences of the welfare state in the core counties and catch-up modernizations in the periphery, concepts such as cronyism and mafioso state were proposed. What these three app...
Um olhar sobre a teoria crítica no Brasil: entrevista com Gabriel Cohn
Musse, Ricardo; Klein, StefanEntrevista com Gabriel Cohn sobre a teoria crítica no Brasil.; Interview with Gabriel Cohn about critical theory in Brazil
Apresentação ao Dossiê - Teoria crítica
Musse, Ricardo; Klein, StefanApresentação ao Dossiê - Teoria crítica; Introduction to Dossier - Critical Theory
Niklas Luhmann. Sistemas sociais: esboço de uma teoria geral
Klein, StefanResenha crítica da obra Sistemas sociais: Esboço de uma Teoria Geral, de Niklas Luhmann.; Review of the book Social Systems, by Niklas Luhmann
Veredas da mudança na ciência brasileira
Klein, Stefan; Toledo Ferreira, MarianaReview of: Maria Caramez Carlotto, Veredas da mudança na ciência brasileira: discurso, institucionalização e práticas no cenário contemporâneo. São Paulo, Scientiae Studia/34, 2013. 379 pp.