4 documents found, page 1 of 1
Genomic selection for boar taint compounds and carcass traits in a commercial p...
Campos, Carolina Filardi de; Lopes, Marcos Soares; Silva, Fabyano Fonseca e; Veroneze, Renata; Knol, Egbert F.; Lopes, Paulo SávioThis study aimed to compare two different Genome-Wide Selection (GWS) methods (Ridge Regression BLUP − RR-BLUP and Bayesian LASSO − BL) to predict the genomic estimated breeding values (GEBV) of four phenotypes, including two boar taint compounds, i.e., the concentrations of androstenone (andro) and skatole (ska), and two carcass traits, i.e., backfat thickness (fat) and loin depth (loin), which were measured i...
Weighted single-step GWAS and gene network analysis reveal new candidate genes ...
Marques, Daniele B. D.; Bastiaansen, John W. M.; Broekhuijse, Marleen L. W. J.; Lopes, Marcos S.; Knol, Egbert F.; Harlizius, BarbaraIn recent years, there has been increased interest in the study of the molecular processes that affect semen traits. In this study, our aim was to identify quantitative trait loci (QTL) regions associated with four semen traits (motility, progressive motility, number of sperm cells per ejaculate and total morphological defects) in two commercial pig lines (L1: Large White type and L2: Landrace type). Since the ...
Gene networks for total number born in pigs across divergent environments
Verardo, Lucas L.; Lopes, Marcos S.; Mathur, Pramod; Madsen, Ole; Silva1, Fabyano F.; Groenen, Martien A. M.; Knol, Egbert F.; Lopes, Paulo S.For reproductive traits such as total number born (TNB), variance due to different environments is highly relevant in animal breeding. In this study, we aimed to perform a gene-network analysis for TNB in pigs across different environments using genomic reaction norm models. Thus, based on relevant single-nucleotide polymorphisms and linkage disequilibrium blocks across environments obtained from GWAS, differen...
Revealing new candidate genes for reproductive traits in pigs: combining Bayesi...
Verardo, Lucas L.; Silva, Fabyano F.; Lopes, Marcos S.; Madsen, Ole; Bastiaansen, John W. M.; Knol, Egbert F.; Kelly, Mathew; Varona, LuisReproductive traits such as number of stillborn piglets (SB) and number of teats (NT) have been evaluated in many genome-wide association studies (GWAS). Most of these GWAS were performed under the assumption that these traits were normally distributed. However, both SB and NT are discrete (e.g. count) variables. Therefore, it is necessary to test for better fit of other appropriate statistical models based on ...