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Cytokine expression in the duodenal mucosa of patients with visceral leishmaniasis

Luz,Kleber Giovanni; Tuon,Felipe Francisco; Duarte,Maria Irma Seixas; Maia,Guilherme Mariz; Matos,Paulo; Ramos,Ana Maria de Oliveira

INTRODUCTION: Visceral leishmaniasis (VL) is a neglected tropical disease with a complex immune response in different organs. This pattern of organ-specific immune response has never been evaluated in the gastrointestinal tract. The aim of this study was to determine the in situ immune response in duodenal biopsies on patients with VL. METHODS: A case-control study was conducted on 13 patients with VL in compar...

Date: 2010   |   Origin: Oasisbr
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Um caso de leishmaniose cutâneo-mucosa tratado com sucesso com baixa dose de an...

Amato,Valdir Sabbaga; Oliveira,Luciana Silveira de; Silva,Anita Campos Mendonça; Machado,Flávia Ribeiro; Amato,Juliane Gomes de Paula

Os autores relatam um caso de leishmaniose cutâneo-mucosa em uma paciente de 89 anos, diabética e hipertensa, tratada inicialmente com alopurinol por 10 meses não havendo cicatrização das lesões. Posteriormente, recebeu antimoniato de N-metil glucamina (glucantime) por 4 dias, na dose total de 2.380mg do Sb v, mas desenvolveu cardiotoxicidade e hipocalemia, sendo suspenso o tratamento, entretanto, evoluiu com r...

Date: 1998   |   Origin: Oasisbr
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