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Phytosterols: From Preclinical Evidence to Potential Clinical Applications

Salehi, B; Quispe, C; Sharifi-Rad, J; Martins, N; Nigam, M; Mishra, AP; Konovalov, DA; Orobinskaya, V; Abu-Reidah, IM; Zam, W; Sharopov, F; Venneri, T

Phytosterols (PSs) are plant-originated steroids. Over 250 PSs have been isolated, and each plant species contains a characteristic phytosterol composition. A wide number of studies have reported remarkable pharmacological effects of PSs, acting as chemopreventive, anti-inflammatory, antioxidant, antidiabetic, and antiatherosclerotic agents. However, PS bioavailability is a key issue, as it can be influenced by...


Bioactive Compounds as Potential Agents for Sexually Transmitted Diseases Manag...

Sharifi-Rad, J; Quispe, C; Rahavian, A; Pereira Carneiro, JN; Rocha, JE; Alves Borges Leal, AL; Bezerra Morais Braga, MF; Melo Coutinho, HD

Sexually transmitted diseases (STDs) are produced by pathogens like bacteria, fungi, parasites, and viruses, and may generate severe health problems such as cancer, ulcers, and even problems in the newborn. This narrative review aims to present updated information about the use of natural bioactive compounds for the prevention and treatment of sexually transmitted infections. A search of the literature was perf...


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