13 documents found, page 1 of 2
Clinical correlates and prognostic impact of neurologic disorders in Takotsubo ...
Cammann, Victoria L.; Scheitz, Jan F.; von Rennenberg, Regina; Jäncke, Lutz; Nolte, Christian H.; Szawan, Konrad A.; Stengl, Helena; Würdinger, MichaelCardiac alterations are frequently observed after acute neurological disorders. Takotsubo syndrome (TTS) represents an acute heart failure syndrome and is increasingly recognized as part of the spectrum of cardiac complications observed after neurological disorders. A systematic investigation of TTS patients with neurological disorders has not been conducted yet. The aim of the study was to expand insights rega...
Impact of atrial fibrillation on outcome in Takotsubo syndrome: data from the I...
El‐Battrawy, Ibrahim; Cammann, Victoria L.; Kato, Ken; Szawan, Konrad A.; Di Vece, Davide; Rossi, Aurelio; Wischnewsky, Manfred; Hermes‐Laufer, JuliaBackground Atrial fibrillation (AF) is a major risk factor for mortality. The prevalence, clinical correlates, and prognostic impact of AF in Takotsubo syndrome (TTS) have not yet been investigated in a large patient cohort. This study aimed to investigate the prevalence, clinical correlates, and prognostic impact of AF in patients with TTS. Methods and Results Patients with TTS were enrolled from the Internati...
Ethnic comparison in takotsubo syndrome : novel insights from the International...
Imori, Yoichi; Kato, Ken; Cammann, Victoria L.; Szawan, Konrad A.; Wischnewsky, Manfred; Dreiding, Sara; Würdinger, Michael; Schönberger, MaximilianBackground: Ethnic disparities have been reported in cardiovascular disease. However, ethnic disparities in takotsubo syndrome (TTS) remain elusive. This study assessed differences in clinical characteristics between Japanese and European TTS patients and determined the impact of ethnicity on in-hospital outcomes. Methods: TTS patients in Japan were enrolled from 10 hospitals and TTS patients in Europe were enr...
Prognostic impact of acute pulmonary triggers in patients with Takotsubo syndro...
Kato, Ken; Cammann, Victoria L.; Napp, L. Christian; Szawan, Konrad A.; Micek, Jozef; Dreiding, Sara; Levinson, Rena A.; Petkova, VanyaAims: Acute pulmonary disorders are known physical triggers of takotsubo syndrome (TTS). This study aimed to investigate prevalence of acute pulmonary triggers in patients with TTS and their impact on outcomes. Methods and results: Patients with TTS were enrolled from the International Takotsubo Registry and screened for triggering factors and comorbidities. Patients were categorized into three groups (acute pu...
Cost-effectiveness of low-dose colchicine after myocardial infarction in the Co...
Samuel, Michelle; Tardif, Jean-Claude; Khairy, Paul; Roubille, François; Waters, David D; Grégoire, Jean C; Pinto, Fausto J.; Maggioni, Aldo P.Aims: In the randomized, placebo-controlled Colchicine Cardiovascular Outcomes Trial (COLCOT) of 4745 patients enrolled within 30 days after myocardial infarction (MI), low-dose colchicine (0.5 mg once daily) reduced the incidence of the primary composite endpoint of cardiovascular death, resuscitated cardiac arrest, MI, stroke, or urgent hospitalization for angina leading to coronary revascularization. To asse...
Pharmacogenomics of the efficacy and safety of Colchicine in COLCOT
Dubé, Marie-Pierre; Legault, Marc-André; Lemaçon, Audrey; Lemieux Perreault, Louis-Philippe; Fouodjio, René; Waters, David D.; Kouz, SimonBackground: The randomized, placebo-controlled COLCOT (Colchicine Cardiovascular Outcomes Trial) has shown the benefits of colchicine 0.5 mg daily to lower the rate of ischemic cardiovascular events in patients with a recent myocardial infarction. Here, we conducted a post hoc pharmacogenomic study of COLCOT with the aim to identify genetic predictors of the efficacy and safety of treatment with colchicine. Met...
Coexistence and outcome of coronary artery disease in Takotsubo syndrome
Templin, Christian; Ghadri, Jelena R; Ruschitzka, Frank; Lüscher, Thomas F; Braunwald, Eugene; Bauersachs, Johann; Bax, Jeroen J; Münzel, ThomasAims: Takotsubo syndrome (TTS) is an acute heart failure syndrome, which shares many features with acute coronary syndrome (ACS). Although TTS was initially described with angiographically normal coronary arteries, smaller studies recently indicated a potential coexistence of coronary artery disease (CAD) in TTS patients. This study aimed to determine the coexistence, features, and prognostic role of CAD in a l...
Intraventricular thrombus formation and embolism in Takotsubo syndrome
Ding, Katharina J.; Cammann, Victoria L.; Szawan, Konrad A.; Stähli, Barbara E.; Wischnewsky, Manfred; Di Vece, Davide; Citro, RodolfoObjective: Takotsubo syndrome (TTS) is characterized by acute left ventricular dysfunction, which can contribute to intraventricular thrombus and embolism. Still, prevalence and clinical impact of thrombus formation and embolic events on outcome of TTS patients remain unclear. This study aimed to investigate clinical features and outcomes of patients with and without intraventricular thrombus or embolism. Addit...
Age-related variations in Takotsubo syndrome
Cammann, Victoria L.; Szawan, Konrad A.; Stähli, Barbara E.; Kato, Ken; Budnik, Monika; Wischnewsky, Manfred; Dreiding, Sara; Levinson, Rena A.BACKGROUND: Takotsubo syndrome (TTS) occurs predominantly in post-menopausal women but is also found in younger patients. OBJECTIVES: This study aimed to investigate age-related differences in TTS. METHODS: Patients diagnosed with TTS and enrolled in the International Takotsubo Registry between January 2011 and February 2017 were included in this analysis and were stratified by age (younger: #50 years, middle-a...
Time-to-treatment initiation of colchicine and cardiovascular outcomes after my...
Bouabdallaoui, Nadia; Tardif, Jean-Claude; Waters, David D.; Pinto, Fausto J.; Maggioni, Aldo P.; Diaz, Rafael; Berry, Colin; Koenig, WolfgangAims: The COLchicine Cardiovascular Outcomes Trial (COLCOT) demonstrated the benefits of targeting inflammation after myocardial infarction (MI). We aimed to determine whether time-to-treatment initiation (TTI) influences the beneficial impact of colchicine. Methods and results: In COLCOT, patients were randomly assigned to receive colchicine or placebo within 30 days post-MI. Time-to-treatment initiation was d...