Made available in DSpace on 2022-04-28T17:23:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-15; Ceftriaxone sodium is a widely used antimicrobial, which is only available as a lyophilized powder. The presence of methods for evaluating the quality of this product is very important and helps to ensure its effectiveness, in addition to contributing to the fight against bacterial resistance. Therefore...
Made available in DSpace on 2022-04-29T08:35:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-08-20; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); BACKGROUND: Rifaximin, a semi-synthetic antimicrobial, does not present microbiological method described in official compendia, and there is a lack of literature on this topic. The quality control of antimicrobials is extremely important to ...
Made available in DSpace on 2021-06-25T10:13:03Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); This work reports the mechanochemical synthesis and characterization of a cocrystal formed by norfloxa...
Made available in DSpace on 2021-06-25T10:49:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01; Dexamethasone acetate (DEX), a potent anti-inflammatory, is used primarily in the treatment of inflammatory and autoimmune diseases. It was incorporated in CETETH 20 (polyoxyethylene 20 cetyl alcohol)–based liquid crystalline systems to enhance the purpose of the drug. Concomitant with the pharmaceutica...
Made available in DSpace on 2021-06-25T10:57:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-05; BACKGROUND: Ceftriaxone sodium, an antimicrobial used in parenteral form, does not have a microbiological method by turbidimetry described in the literature. For drugs from antimicrobial class, the existence of a microbiological method for assessing their potency is essential. Not only are the results f...
Made available in DSpace on 2021-06-25T10:25:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Cocrystallization is a very efficient strategy to improve the physicochemical properties of bioactive agents. A new norfloxacin (NOR)–saccharin cocrystal and a cocrystal–solvate were synthesized through the mechanochemical method (neat and liquid-assisted grinding), and the characterization was performe...
Made available in DSpace on 2018-12-11T16:53:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-29; Bacterial resistance is a growing and worrying factor. The high reproducibility of these resistant microorganisms tends to influence the development of new drugs and research related to product quality control. Among the existing antimicrobials, flucloxacillin (FLU) was designed for oral and injectable ...