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Burden of disease attributable to risk factors in European countries: a scoping...

Gorasso, V; Morgado, JN; Charalampous, P; Pires, SM; Haagsma, JA; Santos, JV; Idavain, J; Ngwa, CH; Noguer, I; Padron-Monedero, A; Sarmiento, R

Objectives Within the framework of the burden of disease (BoD) approach, disease and injury burden estimates attributable to risk factors are a useful guide for policy formulation and priority setting in disease prevention. Considering the important differences in methods, and their impact on burden estimates, we conducted a scoping literature review to: (1) map the BoD assessments including risk factors perfor...


Bruton's tyrosine kinase inhibition—An emerging therapeutic strategy in immune‐...

Mendes‐Bastos, P; Brasileiro, A; Kolkhir, P; Frischbutter, S; Scheffel, J; Moñino‐Romero, S; Maurer, M

Bruton's tyrosine kinase (BTK), a member of the Tec kinase family, is critically involved in a range of immunological pathways. The clinical application of BTK inhibitors for B-cell malignancies has proven successful, and there is strong rationale for the potential benefits of BTK inhibitors in some autoimmune and allergic conditions, including immune-mediated dermatological diseases. However, the established r...

Date: 2022   |   Origin: Saúde - CUF

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