5 documents found, page 1 of 1
Oral Nodular Lesions in Patients with Sjögren’s Syndrome: Unusual Oral Implicat...
Pinheiro,Juliana Barchelli; Tirapelli,Camila; Silva,Claudia Helena Lovato da; Komesu,Marilena Chinali; Petean,Flávio Calil; Louzada Junior,PauloAbstract Sjögren’s syndrome (SS) is a systemic chronic autoimmune disorder affecting the lacrimal and salivary glands. SS may manifest as primary SS (pSS) or secondary SS (sSS), the latter occurring in the context of another autoimmune disorder. In both cases, the dry eyes and mouth affect the patient’s quality of life. Late complications may include blindness, dental tissue destruction, oral candidiasis and ly...
Oral coinfection can stress peripheral lymphocyte to inflammatory activity in l...
Motta,Ana Carolina Fragoso; Simão,João Carlos Lopes; Furini,Renata Bazan; Ferreira,Maria Aparecida Nunes; Palma,Patrícia Vianna BoniniINTRODUCTION: This study evaluated the intracellular profile of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-10 (IL-10) and interferon-γ (IFN-γ) in peripheral blood mononuclear cells (PBMCs) from leprosy patients based on oral infections presence to determine whether these coinfections could be associated with pro-inflammatory activity in leprosy. METHODS: Leprosy patients regardless of clinical form...
Could leprosy reaction episodes be exacerbated by oral infections?
Motta,Ana Carolina Fragoso; Furini,Renata Bazan; Simão,João Carlos Lopes; Vieira,Mariana Bellini; Ferreira,Maria Aparecida NunesINTRODUCTION: This study evaluated whether leprosy reactions could be associated with oral infection. METHODS: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after ...
Double-blind, crossover, placebo-controlled clinical trial with clobetasol prop...
Motta,Ana Carolina Fragoso; Domaneschi,Carina; Komesu,Marilena Chinali; Souza,Cacilda da Silva; Aoki,Valéria; Migliari,Dante AntonioThe aim of this study was to evaluate the efficacy of a 0.05% clobetasol propionate ointment administered in trays to 22 patients with desquamative gingivitis in a double-blind, crossover, placebo-controlled trial. Patients received container number 1 and were instructed to apply the ointment 3 times a day for 2 weeks, and to reduce the application to once a day in the third week. Next, the patients were then i...
Corticosteróide tópico oclusivo no tratamento de manifestações gengivais de doe...
Motta,Ana Carolina Fragoso; Komesu,Marilena Chinali; Grisi,Márcio Fernando de Moraes; Souza,Cacilda da Silva; Roselino,Ana Maria FerreiraO tratamento das lesões gengivais de doenças vesicobolhosas auto-imunes constitui grande desafio na estomatologia, principalmente pela natureza crônica das lesões. O tratamento sistêmico é necessário no controle das apresentações mais graves; entretanto, quando possível, o tratamento tópico é preferível. Este artigo descreve uma técnica oclusiva para aplicação de corticosteróide tópico que tem demonstrado ser e...