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22β-hydroxytingenone induces apoptosis and suppresses invasiveness of melanoma ...
Aranha, Elenn Suzany Pereira; Portilho, Adrhyann Jullyanne de Sousa; Sousa, Leilane Bentes de; Silva, Emerson Lucena da; Mesquita, Felipe PantojaEthnopharmacological relevance: 22β-hydroxytingenone (22-HTG) is a quinonemethide triterpene isolated from Salacia impressifolia (Miers) A. C. Smith (family Celastraceae), which has been used in traditional medicine to treat a variety of diseases, including dengue, renal infections, rheumatism and cancer. However, the anticancer effects of 22-HTG and the underlying molecular mechanisms in melanoma cells have no...
Integrative analysis based on HPLC-DAD-MS/MS and NMR of Bertholletia excelsa Ba...
Silva, Felipe Moura Araújo da; Hanna, Anna Carolina S.; Souza, Abraão A. de; Silva-Filho, Francinaldo A. da; Canhoto, Olinda M.F.; Magalhães, AlviclerBertholletia excelsa Bonpl. (Lecythidaceae) is a South American tree worldwide known for providing the Brazil nuts. In the Amazon Region, B. excelsa is found in monocultures, integrating agroforestries and providing raw materials for food and timber industries. Through the application of an integrative analysis based on high-performance liquid chromatography coupled with diode array detector and tandem mass spe...
Aproveitamento do Óleo das Amêndoas de Tucumã do Amazonas na Produção de Biodiesel
Barbosa, Banny Silva; Koolen, Hector Henrique Ferreira; Barreto, Andreza Cruz; Silva, João Domingos da; Figliuolo, Roberto; Nunomura, Sergio MassayoshiA falta de disponibilidade de energia elétrica é um dos principais motivos pelo baixo Índice de Desenvolvimento Humano das comunidades isoladas localizadas na Amazônia. O biodiesel produzido a partir de óleos vegetais extraídos de espécies oleaginosas nativas de forma sustentada é uma das melhores alternativas energéticas para a região. O tucumã do amazonas, Astrocaryum aculeatum, é uma espécie de palmeira que ...
Gas chromatography coupled to high resolution time-of-flight mass spectrometry ...
Koolen, Hector Henrique Ferreira; Klitzke, Clécio Fernando; Binkley, Joe; Patrick, Jeffrey; Albergaria-Barbosa, Ana Cecília Rizzatti deSubmitted by Gisele Mara Hadlich (gisele@ufba.br) on 2019-05-14T17:03:42Z No. of bitstreams: 1 2560498.pdf: 1993203 bytes, checksum: 2ec5f619479cc1fe308a40801a77d077 (MD5); Approved for entry into archive by Jessica Alves (alves.jessica@ufba.br) on 2019-05-29T19:45:05Z (GMT) No. of bitstreams: 1 2560498.pdf: 1993203 bytes, checksum: 2ec5f619479cc1fe308a40801a77d077 (MD5); Made available in DSpace on 2019-05-29T...
Calycophyllum spruceanum BENTH ameliorates acute inflammation in mice
Silva, Ana Paula Azevedo Barros da; Amorim, Renata Morais Ferreira; Lopes, Roberta de Freitas; Mota, Mário Rogério Lima; Silva, Felipe Moura Araújo daEthnopharmacological relevance: Calycophyllum spruceanum (Benth.) Hook. F. ex K. Schum. is widely distributed in the Amazonian region of Brazil, where it is popularly known as “mulateiro”, “pau-mulato”, “pau-mulato-devárzea”, “escorrega-macaco” or “pau-marfim”. Preparations of C. spruceanum barks are used in the form of tea, poultice or skin patches to treat stomach diseases, skin inflammation and uterus tumors...
Cinerascetins, new peptides from Hypsiboas cinerascens : MALDI LIFT-TOF-MS/MS d...
Almeida, Richardson Alves de; Gordo, Marcelo; Silva, Felipe Moura Araujo da; Araújo, Rafael C. de; Ramada, Marcelo Henrique Soller; Abrão, Fernando YanoThe continuous search for antimicrobial candidates pushes the pursuit of compounds in the most diverse organisms. Amphibians are known as a prolific source of antibacterial peptides. Based on the rich biodiversity of the Amazon region the unexplored green-tree frog (Hypsiboas cinerascens) was studied for its skin secretion peptide content. Chromatographic separations and established tandem mass spectrometry (MS...