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Erlangen Score as a tool to predict progression from mild cognitive impairment ...

Baldeiras, I; Santana, I; Leitão, MJ; Vieira, D; Duro, D; Mroczko, B; Kornhuber, J; Lewczuk, P

BACKGROUND: The previously described and validated Erlangen Score (ES) algorithm enables interpretation of the cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD), ordering them on an ordinal scale: from neurochemically normal (ES = 0) through improbable AD (ES = 1), possible AD (ES = 2 or 3), to probable AD (ES = 4). Here we assess the accuracy of the ES in predicting hazards of progression from t...


Consensus Paper of the WFSBP Task Force on Biological Markers of Dementia: the ...

Wiltfang, J; Lewczuk, P; Riederer, P; Grünblatt, E; Hock, C; Scheltens, P; Hampel, H; Vanderstichele, H; Iqbal, K; Galasko, D; Lannfelt, L; Otto, M

Aging of population, and increasing life expectancy result in an increasing number of patients with dementia. This symptom can be a part of a completely curable disease of the central nervous system (e.g, neuroinflammation), or a disease currently considered irreversible (e.g, Alzheimer's disease, AD). In the latter case, several potentially successful treatment approaches are being tested now, demanding reason...

Date: 2009   |   Origin: Oasisbr

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