Made available in DSpace on 2022-04-28T19:45:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01; The genetic predisposition to head and neck carcinomas (HNSCC) and how the known risk factors (papillomavirus infection, alcohol, and tobacco consumption) contribute to the early-onset disease are barely explored. Although HNSCC at early onset is rare, its frequency is increasing in recent years. Germli...
Made available in DSpace on 2022-04-28T19:56:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2005-01-15; Purpose: Genetic biomarkers of head and neck tumors could be useful for distinguishing among patients with similar clinical and histopathologic characteristics but having differential probabilities of survival. The purpose of this study was to investigate chromosomal alterations in head and neck carcino...
Made available in DSpace on 2022-04-28T20:07:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2006-02-01; Aberrant methylation of seven potential binding sites of the CTCF factor in the differentially methylated region upstream of the H19 gene (H19-DMR) has been suggested as critical for the regulation of IGF2 and H19 imprinted genes. In this study, we analyzed the allele-specific methylation pattern of CTC...