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Cushing’s syndrome due to ectopic adrenocorticotropin secretion by a parotid ca...

Antonacio,Fernanda F.; Harada,Guilherme; Vilela,Rafael S.; Freitas,Thais C.; Lima Jr.,Jose V.; Kowalski,Luiz Paulo; Almeida,Madson Q.

SUMMARY We report a rare case of Cushing’s syndrome in a 37-year-old female who initially presented with localized acinic cell carcinoma of the parotid gland. In January 2014, she underwent a right parotidectomy with facial nerve preservation and adjuvant radiotherapy. In August 2018, she presented a histologically-proven local regional relapse. The patient was considered for salvage surgery with facial nerve s...

Date: 2022   |   Origin: Oasisbr

Decreased CD1a + and CD83 + cells in tonsillar squamous cell carcinoma regardle...

Gama-Cuellar,Ana Guadalupe; Francisco,Ana Lúcia Noronha; Scarini,João Figueira; Mariano,Fernanda Viviane; Kowalski,Luiz Paulo; Gondak,Rogério

Abstract Dendritic cells (DCs) are specialized antigen-presenting cells that play a critical role in the immune response against human papillomavirus (HPV) infection, and represent a therapeutic target in cancer. Objective: To identify and quantify DCs in tonsillar squamous cell carcinoma (TSCC) under the influence of HPV infection. Methodology: CD1a and CD83 antibodies were used to identify immature dendritic ...

Date: 2022   |   Origin: Oasisbr

Trans Oral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) in Brazil: Saf...

Bertelli,Antonio Augusto Tupinambá; Rangel,Leonardo Guimarães; Lira,Renan Bezerra; Tesseroli,Marco Antonio Scirea; Santos,Izabella Costa

ABSTRACT Background: The aim of this study was to address the first cases of TOETVA done in Brazil, by TOETVA-Bra study group, regarding safety and complications. Materials and Methods: Series of the first 93 TOETVAs cases in Brazil. All authors except LPK, AJG JOR and RPT received TOETVA training including cadaveric hands-on in Thailand or United States (Johns Hopkins Medicine) during 2017. After they came bac...

Date: 2021   |   Origin: Oasisbr

The Impact of the COVID-19 Pandemic on Head and Neck Surgery Training: A Brazil...

Leite,Ana Kober; Matos,Leandro Luongo; Cernea,Claudio R.; Kowalski,Luiz Paulo

Abstract Introduction The COVID-19 pandemic has had a high impact on surgical training around the world due to required measures regarding the suspension of elective procedures and the dismissal of nonessential personnel. Objectives To understand the impact the pandemic had on head and neck surgery training in Brazil. Methods We conducted a 29-question online survey with head and neck surgery residents in Brazi...

Date: 2021   |   Origin: Oasisbr

Risk Factors and Outcomes of Postoperative Neck Hematomas: An Analysis of 5,900...

de Carvalho,Andre Ywata; Gomes,Camila Couto; Chulam,Thiago Celestino; Vartanian,Jose Guilherme; Carvalho,Genival Barbosa; Lira,Renan Bezerra

Abstract Introduction Postoperative neck hematoma (PNH) is an uncommon but potentially-lethal complication of thyroid surgery. Objective To identify the risk factors for postthyroidectomy hematoma requiring reoperation, the timing, the source of the bleeding, the related respiratory distress requiring tracheotomy, and the late outcomes. Methods We retrospectively analyzed the records of 5,900 consecutive patien...

Date: 2021   |   Origin: Oasisbr

Predictive Factors of Recurrence of Papillary Thyroid Microcarcinomas: Analysis...

Carvalho,Andre de Ywata; Kohler,Hugo Fontan; Gomes,Camila Couto; Vartanian,José Guilherme; Kowalski,Luiz Paulo

Abstract Introduction The incidence of papillary thyroid microcarcinoma (PTMC) has increased, and its treatment remains controversial. Objective To identify the clinical and pathological factors predictive of tumor recurrence. Methods We retrospectively analyzed 2,538 consecutive patients treated for PTMC, most submitted to total thyroidectomy (98%) followed by radioactive iodine (RAI) ablation (51.7%) at a can...

Date: 2021   |   Origin: Oasisbr

Effect of the COVID-19 Pandemic on the Activity of Physicians Working in the Ar...

Kowalski,Luiz Paulo; Imamura,Rui; Castro Junior,Gilberto de; Marta,Gustavo Nader; Chaves,Aline Lauda Freitas; Matos,Leandro Luongo

Abstract Introduction Coronavirus disease 2019 (COVID-19) is an acute infection caused by the new coronavirus (SARS-CoV-2) and it is highly transmissible, especially through respiratory droplets. To prepare the health system for the care of these patients also led to a restriction in the activity of several medical specialties. Physicians who work with patients affected by diseases of the head and neck region c...

Date: 2020   |   Origin: Oasisbr

Preoperative vitamin D deficiency is a risk factor for postoperative hypocalcem...

Carvalho,Genival Barbosa de; Giraldo,Lina Restrepo; Lira,Renan Bezerra; Macambira,Isabela Bergh Martins; Tapia,Marcel Adalid; Kohler,Hugo Fontan

ABSTRACT BACKGROUND: The relationship between preoperative vitamin D deficiency and postoperative hypocalcemia in cases of total thyroidectomy (TT) is a matter of controversy and may vary according to geographical scenarios and populations. OBJECTIVE: The objective here was to evaluate whether preoperative vitamin D deficiency was associated with postoperative symptomatic hypocalcemia in a population in South A...

Date: 2019   |   Origin: Oasisbr

Oral squamous cell carcinoma: a clinicopathological study on 194 cases in north...

Leite,Amanda Almeida; Leonel,Augusto César Leal da Silva; Castro,Jurema Freire Lisboa de; Carvalho,Elaine Judite de Amorim; Vargas,Pablo Agustin

ABSTRACT BACKGROUND: Only a few studies have evaluated the clinicopathological features of oral squamous cell carcinoma (SCC) in Brazil, and most were conducted in the most industrialized region of the country, i.e. the southeastern region. The aim of this study was to evaluate the clinicopathological features of this malignant neoplasm in northeastern Brazil. DESIGN AND SETTING: Retrospective study performed i...

Date: 2018   |   Origin: Oasisbr

Patient Concerns Inventory for head and neck cancer: Brazilian cultural adaptation

Jungerman,Ivy; Toyota,Julia; Montoni,Neyller Patriota; Azevedo,Elma Heitmann Mares; Guedes,Renata Ligia Vieira; Damascena,Aline; Lowe,Derek

Summary Objective: The purpose of this study was to translate, culturally validate and evaluate the Patients Concerns Inventory - Head and Neck (PCI-H&N) in a consecutive series of Brazilian patients. Method: This study included adult patients treated for upper aerodigestive tract (UADT) cancer. The translation and cultural adaptation of the PCI-H&N followed internationally accepted guidelines and included a pr...

Date: 2017   |   Origin: Oasisbr

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