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Quantification of overdiagnosis in randomised trials of cancer screening

Voss, Theis; Krag, Mikela; Martiny, Frederik; Heleno, Bruno; Jørgensen, Karsten Juhl; Brandt Brodersen, John

OK; The degree of overdiagnosis in common cancer screening trials is uncertain due to inadequate design of trials, varying definition and methods used to estimate overdiagnosis. Therefore, we aimed to quantify the risk of overdiagnosis for the most widely implemented cancer screening programmes and assess the implications of design limitations and biases in cancer screening trials on the estimates of overdiagno...


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