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Analysis of the immune response to Neospora caninum in a model of intragastric ...

Teixeira, L.; Botelho, A. S.; Batista, A. R.; Meireles, C. S.; Ribeiro, A.; Domingues, H. S.; Correia Da Costa, J. M.; Castro, António G.

To study experimental Neospora caninum infection initiated at the gastrointestinal tract, Toll-like Receptor 4- and functional IL-12Rbeta2 chain-deficient C57BL/10 ScCr mice were challenged intragastrically with 5 x 10(6) N. caninum tachyzoites. All parasite-inoculated mice eventually died with disseminated infection. In contrast, immunocompetent BALB/c mice challenged with 1 x 10(7) N. caninum tachyzoites by t...

Date: 2007   |   Origin: RepositóriUM - Universidade do Minho
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