5 documents found, page 1 of 1
Blood antioxidant nutrients in riparian villagers of the Brazilian Amazon: its ...
Valentini,Juliana; Passos,Carlos José Sousa; Garcia,Solange Cristina; Davidson,Robert; Lucotte,Marc; Mertens,Frédéric; Romana,ChristineAbstract This study associates blood antioxidants like copper (Cu), manganese (Mn), selenium (Se), zinc (Zn), β-carotene, lycopene and vitamins (A and E) to sociodemographic features and seasonality in communities from the Tapajós River region, Brazilian Amazon. We observed increased Mn, Se and Zn levels compared to the average Brazilian population, whereas this is only the case for β-carotene in the rainy seas...
Simultaneous quantification of lycopene, β-carotene, retinol and α -tocopherol ...
Charão,Mariele F.; Moro,Angela M.; Brucker,Natália; Bulcão,Rachel P.; Baierle,Marília; Freitas,Fernando; Durgante,Juliano; Nascimento,SabrinaA method for the simultaneous quantification of lycopene, β-carotene, retinol and α-tocopherol by high-performance liquid chromatography (HPLC) with Vis/fluorescence detection with isocratic elution was optimized and validated. The method consists of a rapid and simple liquid-liquid extraction procedure and a posterior quantification of extracted supernatants by HPLC. Aliquots of plasma were stored at -20°C for...
Designer drugs: aspectos analíticos e biológicos
Bulcão,Rachel; Garcia,Solange Cristina; Limberger,Renata Pereira; Baierle,Marília; Arbo,Marcelo Dutra; Chasin,Alice Aparecida da MattaIn the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and improvement of specific and appropriate analytical methods. This work is a review of the literature which summarizes the characteristics of the drugs and the ana...
Quantificação sérica de vitamina C por CLAE-UV e estudo de estabilidade
Baierle,Marília; Bairros,André de; Moreira,Ana Paula; Bulcão,Rachel; Roehrs,Miguel; Freitas,Fernando de; Durgante,Juliano; Brucker,NatáliaVitamin C, an exogenous antioxidant, is essential to human health. In this study, a method was validated to serum vitamin C quantification by HPLC-UV. Its stability with and without the use of tris [2-carboxy-ethyl] phosphine hydrochloride (TCEP), at -20 and -80 °C, in serum and supernatant were also evaluated. Analysis showed r² > 0.99, precision CV% < 15% and % bias < 15%, being linear, precise and accurat...
Possíveis efeitos do cobre sanguíneo sobre parâmetros hematológicos em idosas
Baierle,Marília; Valentini,Juliana; Paniz,Clóvis; Moro,Angela; Barbosa Junior,Fernando; Garcia,Solange CristinaINTRODUÇÃO: O cobre é um elemento traço essencial e sua homeostase é importante, principalmente em idosos, uma vez que seu metabolismo está associado a doenças neurodegenerativas e distúrbios na eritropoiese, entre outros. OBJETIVO: O presente estudo avaliou a associação entre cupremia, parâmetros hematológicos e estresse oxidativo. MATERIAIS E MÉTODOS: Amostras de sangue de 39 mulheres idosas (grupo de estudo)...