4 documents found, page 1 of 1
Swine and poultry pathogens: The complete genome sequences of two strains of My...
Vasconcelos, Ana Tereza; Ferreira, Henrique Bunselmeyer; Bizarro, Cristiano Valim; Bonatto, Sandro L.; Carvalho, Marcos O.; Pinto, Paulo MarcosThis work reports the results of analyses of three complete mycoplasma genomes, a pathogenic (7448) and a nonpathogenic (J) strain of the swine pathogen Mycoplasma hyopneumoniae and a strain of the avian pathogen Mycoplasma synoviae; the genome sizes of the three strains were 920,079 bp, 897,405 bp, and 799,476 bp, respectively. These genomes were compared with other sequenced mycoplasma genomes reported in the...
Epidemiological profile of Zika, Dengue and Chikungunya virus infections identi...
Vieira, Deusilene Souza; Zambenedetti, Miriam Ribas; Requião, Luciana; Borghetti, Ivo Alberto; Luna, Luciano Kleber de SouzaSeveral arboviruses have emerged and/or re-emerged in North, Central and SouthAmerican countries. Viruses from some regions of Africa and Asia, such as the Zika and Chikungunya virus have been introduced in new continents causing major public health problems. The aim of this study was to investigate the presence of RNA from Zika, Dengue and Chikungunya viruses in symptomatic patients from Rondonia, where the ep...
Effect of ionizing radiation exposure on Trypanosoma cruzi ubiquitin-proteasome...
Cerqueira, Paula Gonçalves; Silva, Danielle Gomes Passos; Rocha, João Pedro Vieira da; Mendes, Isabela Cecilia; Oliveira, Karla Andrade detIn recent years, proteasome involvement in the damage response induced by ionizing radiation (IR)became evident. However, whether proteasome plays a direct or indirect role in IR-induced damageresponse still unclear. Trypanosoma cruzi is a human parasite capable of remarkable high tolerance toIR, suggesting a highly efficient damage response system. Here, we investigate the role of T. cruzi pro-teasome in the ...
Analysis of proteasomal proteolysis during the in vitro metacyclogenesis of Try...
Cardoso, Josiane; Lima, Carla de Paula; Leal, Tiago Ferreira; Gradia, Daniela Fiori; Fragoso, Stênio Perdigão; Goldenberg, SamuelProteasomes are large protein complexes, whose main function is to degrade unnecessary or damaged proteins. The inhibition of proteasome activity in Trypanosoma cruzi blocks parasite replication and cellular differentiation. We demonstrate that proteasome-dependent proteolysis occurs during the cellular differentiation of T. cruzi from replicative non-infectious epimastigotes to non-replicative and infectious t...