2 documents found, page 1 of 1
Cardiovascular comorbidities in amyotrophic lateral sclerosis
Pereira, Mariana; Gromicho, Marta; Henriques, Ana; Pronto Laborinho, Ana Catarina; Grosskreutz, Julian; Kuźma-Kozakiewicz, Magdalena; Petri, SusanneBackground: The role of cardiovascular risk factors in amyotrophic lateral sclerosis (ALS) is controversial. A favourable profile has been found in ALS patients, but previous studies have not specifically considered the profile in different disease phenotypes. Methods: Demographic data, smoking habits, lifetime exercise, and medical history including diabetes mellitus, arterial hypertension, hypercholesterolemi...
Emotional lability at disease onset is an independent prognostic factor of fast...
Kuźma-Kozakiewicz, Magdalena; Uysal, Hilmi; Steinbach, Robert; Rödiger, Annekathrin; Petri, Susanne; Grosskreutz, Julian; Gromicho, MartaAmyotrophic lateral sclerosis (ALS) is a fast progressing neurodegenerative disease leading to quadriplegia, anarthria and respiratory insufficiency. A large variety of phenotypes and disability progression requires individually tailored management. Identification of predictors of poor prognosis may not only improve management, but also allow for more precise patients' stratification for clinical trials or rese...