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In major affective disorders, early life trauma predict increased nitro-oxidati...

Moraes, Juliana Brum; Maes, Michael; Roomruangwong, Chutima; Bonifacio, Kamila Landucci; Barbosa, Decio Sabbatini; Vargas, Heber Odebrecht

Early life trauma (ELT) may increase the risk towards bipolar diso rder (BD) and major depression (MDD), disorders associated with activated neuro-oxidative and neuro-nitrosative stress (O&NS) p athways. It has remained elusive whether ELTs are associated with O&NS and which ELTs are associated with disti nct affective disorder phenotypes. This case-control study examined patients with BD ( n = 68) and MDD ( n ...

Date: 2018   |   Origin: Oasisbr
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