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Conifers phytochemicals: A valuable forest with therapeutic potential

Bhardwaj, K; Silva, AS; Atanassova, M; Sharma, R; Nepovimova, E; Musilek, K; Sharma, R; Alghuthaymi, MA; Dhanjal, DS; Nicoletti, M; Sharma, B

Conifers have long been recognized for their therapeutic potential in different disorders. Alkaloids, terpenes and polyphenols are the most abundant naturally occurring phytochemicals in these plants. Here, we provide an overview of the phytochemistry and related commercial products obtained from conifers. The pharmacological actions of different phytochemicals present in conifers against bacterial and fungal i...


Leptospira interrogans outer membrane protein-based nanohybrid sensor for the d...

Verma, V; Kala, D; Gupta, S; Kumar, H; Kaushal, A; Kuca, K; Martins, N; Kumar, D

Leptospirosis is an underestimated tropical disease caused by the pathogenic Leptospira species and responsible for several serious health problems. Here, we aimed to develop an ultrasen-sitive DNA biosensor for the rapid and on-site detection of the Loa22 gene of Leptospira interrogans using a gold nanoparticle–carbon nanofiber composite (AuN/CNF)-based screen-printed electrode. Cyclic voltammetry and electroc...


Applications of fruit polyphenols and their functionalized nanoparticles agains...

Kumar, H; Bhardwaj, K; Martins, N; Nepovimova, E; Oleksak, P; Dhanjal, DS; Bhardwaj, S; Singh, R; Chopra, C; Verma, R; Chauhan, PP; Kumar, D; Kuca, K

The ingestion of contaminated water and food is known to cause food illness. Moreover, on assessing the patients suffering from foodborne disease has revealed the role of microbes in such diseases. Concerning which different methods have been developed for protecting food from microbes, the treatment of food with chemicals has been reported to exhibit an unwanted organoleptic effect while also affecting the nut...


Potential usage of edible mushrooms and their residues to retrieve valuable sup...

Kumar, H; Bhardwaj, K; Sharma, R; Nepovimova, E; Martins, N; Dhanjal, DS; Singh, R; Chopra, C; Verma, R; Abd-Elsalam, KA; Tapwal, A; Musilek, K

Currently, the food and agricultural sectors are concerned about environmental problems caused by raw material waste, and they are looking for strategies to reduce the growing amount of waste disposal. Now, approaches are being explored that could increment and provide value-added products from agricultural waste to contribute to the circular economy and environmental protection. Edible mushrooms have been glob...


Plant prebiotics and their role in the amelioration of diseases

Kaur, AP; Bhardwaj, S; Dhanjal, DS; Nepovimova, E; Martins, N; Kuca, K; Chopra, C; Singh, R; Kumar, H; Sen, F; Kumar, V; Verma, R; Kumar, D

Prebiotics are either natural or synthetic non-digestible (non-)carbohydrate substances that boost the proliferation of gut microbes. Undigested fructooligosaccharides in the large intestine are utilised by the beneficial microorganisms for the synthesis of short-chain fatty acids for their own growth. Although various food products are now recognized as having prebiotic properties, several others, such as almo...


Commercial ICT Smart Solutions for the Elderly: State of the Art and Future Cha...

Frischer, R; Krejcar, O; Maresova, P; Fadeyi, O; Selamat, A; Kuca, K; Tomsone, S; Teixeira, JP; Madureira, J; Melero, FJ

Within a ubiquitous environment, home and office furniture can be maximally utilized to provide ease, especially if the items are designed based on smart technology. For this reason, the acceptance of smart furniture has soared over the years. Given the vast influence of the Internet of Things (IoT) and Industry 4.0 on technological advancement in furniture design, it is imperative to examine information and co...


Role of vacha (Acorus calamus Linn.) in neurological and metabolic disorders: E...

Sharma, V; Sharma, R; Gautam, DNS; Kuca, K; Nepovimova, E; Martins, N

Vacha (Acorus calamus Linn. (Acoraceae)) is a traditional Indian medicinal herb, which is practiced to treat a wide range of health ailments, including neurological, gastrointestinal, respiratory, metabolic, kidney, and liver disorders. The purpose of this paper is to provide a comprehensive up-to-date report on its ethnomedicinal use, phytochemistry, and pharmacotherapeutic potential, while identifying potenti...


Influence of family environment and tobacco addiction: A short report from a po...

Sharma, R; Martins, N; Tripathi, A; Caponnetto, P; Garg, N; Nepovimova, E; Kuca, K; Kumar Prajapati, P

Background: The initiation of tobacco addiction is complex, and several factors contribute to the onset of this behavior. It is presumed that the influence of family environment may pose a key factor in tobacco addiction. Tobacco-use has been highly observed in the Jamnagar district of Saurashtra region of Gujarat, India. No earlier study has focused on determining the pervasiveness of tobacco-use in families o...


Chyawanprash: A traditional indian bioactive health supplement

Sharma, R; Martins, N; Kuca, K; Chaudhary, A; Kabra, A; Rao, M; Prajapati, P

Chyawanprash (CP) is an Ayurvedic health supplement which is made up of a super-concentrated blend of nutrient-rich herbs and minerals. It is meant to restore drained reserves of life force (ojas) and to preserve strength, stamina, and vitality, while stalling the course of aging. Chyawanprash is formulated by processing around 50 medicinal herbs and their extracts, including the prime ingredient, Amla (Indian ...


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