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Physical activity, sedentary behaviour, and childhood asthma: a European collab...

Eijkemans, M; Mommers, M; Harskamp-van Ginkel, MW; Vrijkotte, TGM; Ludvigsson, J; Faresjö, Å; Bergström, A; Ekström, S; Grote, V; Koletzko, B

OBJECTIVES: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. DESIGN: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined. SETTING: Ch...


Early-life respiratory tract infections and the risk of school-age lower lung f...

van Meel, ER; Mensink-Bout, SM; den Dekker, HT; Ahluwalia, TS; Annesi-Maesano, I; Arshad, SH; Baïz, N; Barros, H; von Berg, A; Bisgaard, H

Background Early-life respiratory tract infections might affect chronic obstructive respiratory diseases, but conclusive studies from general populations are lacking. Our objective was to examine if children with early-life respiratory tract infections had increased risks of lower lung function and asthma at school age. Methods We used individual participant data of 150 090 children primarily from the EU Child ...


European birth cohorts for environmental health research

Vrijheid, M; Casas, M; Bergström, A; Carmichael, A; Cordier, S; Eggesbø, M; Eller, E; Fantini, MP; Fernández, MF; Fernández-Somoano, A; Gehring, U

Background: Many pregnancy and birth cohort studies investigate the health effects of early-life environmental contaminant exposure. An overview of existing studies and their data is needed to improve collaboration, harmonization, and future project planning. Objectives: Our goal was to create a comprehensive overview of European birth cohorts with environmental exposure data. Methods: Birth cohort studies were...


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