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Global age-sex-specific mortality, life expectancy, and population estimates in...

Schumacher, AE; Kyu, HH; Aali, A; Abbafati, C; Abbas, J; Abbasgholizadeh, R; Abbasi, MA; Abbasian, M; Abd ElHafeez, S; Abdelmasseh, M; Abd Elsalam, S

Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides n...


Global Chronic Total Occlusion Crossing Algorithm

Wu, EB; Brilakis, ES; Mashayekhi, K; Tsuchikane, E; Alaswad, K; Araya, M; Avran, A; Azzalini, L; Babunashvili, AM; Bayani, B; Behnes, M; Bhindi, R

The authors developed a global chronic total occlusion crossing algorithm following 10 steps: 1) dual angiography; 2) careful angiographic review focusing on proximal cap morphology, occlusion segment, distal vessel quality, and collateral circulation; 3) approaching proximal cap ambiguity using intravascular ultrasound, retrograde, and move-the-cap techniques; 4) approaching poor distal vessel quality using th...

Date: 2021   |   Origin: Lusíadas Saúde

Baseline maps of potentially toxic elements in the soils of Garhwal Himalayas, ...

Kumar, A; Pinto, MC; Candeias, C; Dinis, PA

Geochemical mapping is frequently used to identify the regions of the Planet with critical chemical elements and their natural or anthropogenic sources. In order to understand elements' geochemistry and to identify the area's potentially harmful associations, high-resolution maps of chemical elements, physico-chemical parameters, a noncarcinogenic hazard index, and a potential ecological risk index were modelle...


Lung and Intercostal Upper Abdomen Ultrasonography for Staging Patients with Ov...

Stukan, M; Bugalho, A; Kumar, A; Kowalewska, J; Świetlik, D; Buda, N; Pietrzak-Stukan, M; Dudziak, M

A detailed transabdominal and transvaginal ultrasound examination, performed by an expert examiner, could render a similar diagnostic performance to computed tomography for assessing pelvic/abdominal tumor spread disease in women with epithelial ovarian cancer (EOC). This study aimed to describe and assess the feasibility of lung and intercostal upper abdomen ultrasonography as pretreatment imaging of EOC metas...

Date: 2020   |   Origin: Saúde - CUF

Myricetin bioactive effects: Moving from preclinical evidence to potential clin...

Taheri, Y; Suleria, HAR; Martins, N; Sytar, O; Beyatli, A; Yeskaliyeva, B; Seitimova, G; Salehi, B; Semwal, P; Painuli, S; Kumar, A; Azzini, E

Several flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricet...


Evaluation of nisin and ll-37 antimicrobial peptides as tool to preserve articu...

Najmi, Z; Kumar, A; Scalia, AC; Cochis, A; Obradovic, B; Grassi, FA; Leigheb, M; Lamghari, M; Loinaz, I; Gracia, R; Rimondini, L

Cartilage repair still represents a challenge for clinicians and only few effective therapies are nowadays available. In fact, surgery is limited by the tissue poor self-healing capacity while the autologous transplantation is often forsaken due to the poor in vitro expansion capacity of chondrocytes. Biomaterials science offers a unique alternative based on the replacement of the injured tissue with an artific...


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