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Mental health and burnout syndrome among postgraduate students in medical and m...

Pinho, Rebeca da Nóbrega Lucena; Costa, Thais Ferreira; Silva, Nayane Miranda; Barros-Areal, Adriana F.; Salles, André de Mattos

Background: The COVID-19 pandemic has led to high levels of physical, psychological, and social stress among health care professionals, including postgraduate students in medical and multidisciplinary residencies. This stress is associated with the intense fear of occupational exposure to SARS-CoV-2, the virus known to cause COVID-19. These professionals are at risk of developing physical and mental illnesses n...

Date: 2021   |   Origin: Oasisbr

Leprosy detection rate in patients under immunosuppression for the treatment of...

Barroso, Daniel Holanda; Brandão, Jurema Guerrieri; Andrade, Elaine Silva Nascimento; Correia, Ana Clara Banhatto; Aquino, Danielle Costa

Background: Recently developed immunosuppressive drugs, especially TNF antagonists, may enhance the risk of granulomatous infections, including leprosy. We aimed to evaluate the leprosy detection rate in patients under immunosuppression due to rheumatological, dermatological and gastroenterological diseases. Methods: We performed a systematic review of the literature by searching the PubMed, EMBASE, LILACS, Web...

Date: 2021   |   Origin: Oasisbr

A comprehensive systematic review of leishmaniasis in patients undergoing drug-...

Kurizky, Patricia Shu; Marianelli, Fernanda Ferraço; Cesetti, Mariana Vicente; Damiani, Giovanni; Sampaio, Raimunda Nonata Ribeiro

Immunosuppression is an important risk factor for leishmaniasis. We assessed the clinical profile, geographic distribution and prevalence of leishmaniasis in patients undergoing immunosuppressive therapy for dermatological, rheumatological or gastroenterological autoimmune diseases. We identified relevant studies in PubMed, EMBASE, Scopus, Web of Science and LILACS on July 3rd, 2018. We included articles that r...

Date: 2021   |   Origin: Oasisbr

Enhanced il-6 and il-12b gene expression after SARS-CoV-2 infection in leprosy ...

Morais Júnior, Gilberto Santos; Kurizky, Patricia Shu; Cerqueira, Selma Regina Penha Silva; Barroso, Daniel Holanda; Schulte, Heidi Luise

Experts have called attention to the possible negative impact of the coronavirus disease 2019 (COVID19)–related cytokine storm syndrome on the progression of leprosy-related disabilities. We assessed the frequency of reactional states in patients co-infected with Mycobacterium leprae and severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 (SARS-CoV-2). We consecutively included patients during the firs...

Date: 2021   |   Origin: Oasisbr

Molecular and cellular biomarkers of COVID-19 prognosis : protocol for the pros...

Kurizky, Patricia Shu; Nóbrega, Otávio T.; Soares, Alexandre Anderson de Sousa Munhoz; Aires, Rodrigo Barbosa; Albuquerque, Cleandro Pires de

Background: Since the beginning of the COVID-19 pandemic, the world’s attention has been focused on better understanding the relation between the human host and the SARS-CoV-2 virus, as its action has led to hundreds of thousands of deaths. Objective: In this context, we decided to study certain consequences of the abundant cytokine release over the innate and adaptive immune systems, inflammation, and hemostas...

Date: 2021   |   Origin: Oasisbr

Enhanced il-6 and il-12b gene expression after SARS-CoV-2 infection in leprosy ...

Morais Júnior, Gilberto Santos; Kurizky, Patricia Shu; Cerqueira, Selma Regina Penha Silva; Barroso, Daniel Holanda; Schulte, Heidi Luise

Experts have called attention to the possible negative impact of the coronavirus disease 2019 (COVID-19)–related cytokine storm syndrome on the progression of leprosy-related disabilities. We assessed the frequency of reactional states in patients co-infected with Mycobacterium leprae and severe acute respiratory syndrome (SARS) coronavirus (CoV) 2 (SARS-CoV-2). We consecutively included patients during the fir...

Date: 2021   |   Origin: Oasisbr

SARS-CoV-2/DENV co-infection : a series of cases from the Federal District, Mid...

Schulte, Heidi Luise; Sousa, José Diego Brito; Lacerda, Marcus Vinícius Guimarães de; Naves, Luciana Ansaneli; Gois, Eliana Teles de

Background: Since the novel coronavirus disease outbreak, over 179.7 million people have been infected by SARS-CoV-2 worldwide, including the population living in dengue-endemic regions, particularly Latin America and Southeast Asia, raising concern about the impact of possible co-infections. Methods: Thirteen SARS-CoV-2/DENV co-infection cases reported in Midwestern Brazil between April and September of 2020 a...

Date: 2021   |   Origin: Oasisbr

Detecção do DNA de Leishmania em pacientes com psoríase e/ ou artrite psoriásic...

Kurizky, Patricia Shu

Tese (doutorado)—Universidade de Brasília, Faculdade de Ciências Médicas, Programa de Pós-Graduação em Ciências Médicas, 2019.; Fundamentos: As drogas imunobiológicas revolucionaram o tratamento da psoríase e da artrite psoriásica, entretanto trouxeram o risco do desenvolvimento e reativação de doenças infecciosas, antes controladas pela resposta imune do hospedeiro, como a leishmaniose. Objetivo: Nosso objetiv...

Date: 2020   |   Origin: Oasisbr

The challenge of concomitant infections in the coronavirus disease 2019 pandemi...

Kurizky, Patricia Shu; Cerqueira, Selma Regina Penha Silva; Cunha, Débora Vilela; Albuquerque, Cleandro Pires de; Aires, Rodrigo Barbosa

Coronavirus disease 2019 (COVID-19) was first officially described in Brazil on February 26th, 2020. The accumulation of reports of concomitant infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and pathogens that cause diseases endemic to tropical countries, such as dengue and chikungunya fever, has started to draw attention. Chagas disease and leprosy remain public health problems in...

Date: 2020   |   Origin: Oasisbr

Evaluation of the occurrence of sexual dysfunction and general quality of life ...

Kurizky, Patricia Shu; Martins, Gladys Aires; Carneiro, Jamille Nascimento; Gomes, Ciro Martins; Mota, Licia Maria Henrique da

Background: Psoriasis has a significant impact on quality of life (QoL). Sexual life can also be affected, with sexual dysfunction being reported by 25-70% of patients. Objectives: To determine the occurrence of sexual dysfunction and evaluate QoL in women with psoriasis. Methods: This case-control study included women aged 18-69 years. The validated Brazilian Portuguese versions of the Female Sexual Function I...

Date: 2019   |   Origin: Oasisbr

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