2 documents found, page 1 of 1
Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multic...
Pirnay, Jean-Paul; Djebara, Sarah; Steurs, Griet; Griselain, Johann; Cochez, Christel; De Soir, Steven; Glonti, Tea; Spiessens, An; Vanden Berghe, EmilyIn contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results. Here we present the outcomes of a retrospective observational analysis of the first 100 consecutive cases of personalized BT of difficult-to-treat infections facilitated by a Belgian consortium i...
Phage therapy
Azeredo, Joana; Pirnay, Jean-Paul; Pires, Diana Priscila Penso; Kutateladze, Mzia; Dabrowska, Krystyna; Lavigne, Rob; Blasdel, Bob G.Phage therapy refers to the use of bacteriophages (phages - bacterial viruses) as therapeutic agents against infectious bacterial diseases. This therapeutic approach emerged in the beginning of the 20th century but was progressively replaced by the use of antibiotics in most parts of the world after the second world war. More recently however, the alarming rise of multidrug-resistant bacteria and the consequent...