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Bioprospection of the antarctic diatoms craspedostauros ineffabilis IMA082A and...

Trentin, Riccardo; Moschin, Emanuela; L, Custódio; Moro, Isabella

In extreme environments such as Antarctica, a diverse range of organisms, including diatoms, serve as essential reservoirs of distinctive bioactive compounds with significant implications in pharmaceutical, cosmeceutical, nutraceutical, and biotechnological fields. This is the case of the new species Craspedostauros ineffabilis IMA082A and Craspedostauros zucchellii IMA088A Trentin, Moschin, Lopes, Custódio and...


Seasonal and geographic dynamics in bioproperties and phytochemical profile of ...

Pereira, Catarina Guerreiro; Rodrigues, Maria João; Nawrot-Hadzik, Izabela; Matkowski, Adam; L, Custódio

This study delved into the influence of ecological and seasonal dynamics on the synthesis of secondary metabolites in the medicinal halophyte Limonium algarvense Erben, commonly known as sea lavender, and examined their antioxidant and anti-inflammatory properties. Aerial parts of sea lavender were systematically collected across winter, spring, summer, and autumn seasons from distinct geographic locations in s...


Exploring the potential of using Marine-Derived Ingredients: From the extractio...

Costa, João Pedro; L, Custódio; Reis, Catarina Pinto

The growing understanding and knowledge of the potential of marine species, as well as the application of “blue biotechnology” have been motivating new innovative solutions in cosmetics. It is widely noted that that marine species are important sources of compounds with several biological activities that are yet to be discovered. This review explores various biological properties of marine-derived molecules and...


New insights into the phytochemical profile and biological properties of Lycium...

Bendjedou, Houaria; Benamar, Houari; Bennaceur, Malika; Rodrigues, Maria João; Pereira, Catarina Guerreiro; Trentin, Riccardo; L, Custódio

This work aimed to boost the valorisation of Lycium intricatum Boiss. L. as a source of high added value bioproducts. For that purpose, leaves and root ethanol extracts and fractions (chloroform, ethyl acetate, n-butanol, and water) were prepared and evaluated for radical scavenging activity (RSA) on 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,20 -azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical...


Bioactive extracts from Salicornia ramosissima J. woods biorefinery as a source...

Hulkko, Laura Sini Sofia; Rocha, Rui Miranda; Trentin, Riccardo; Fredsgaard, Malthe; Chaturvedi, Tanmay; L, Custódio; Thomsen, Mette Hedegaard

Salt-tolerant plants, also known as halophytes, could provide a novel source of feedstock for biorefineries. After harvesting fresh shoots for food, the lignified fraction of Salicornia ramosissima J. Woods could be used to produce bioactive botanical extracts for high-value industries such as nutraceuticals, cosmetics, and biopharmaceuticals. The residual fraction after extraction can be further used for bioen...


Salt-tolerant plants as sources of Antiparasitic Agents for human use: A compre...

Rodrigues, Maria João; Pereira, Catarina Guerreiro; Oliveira, Marta; Zengin, Gökhan; L, Custódio

Parasitic diseases, especially those caused by protozoans and helminths, such as malaria, trypanosomiasis, leishmaniasis, Chagas disease, schistosomiasis, onchocerciasis, and lymphatic filariasis, are the cause of millions of morbidities and deaths every year, mainly in tropical regions. Nature has always provided valuable antiparasitic agents, and efforts targeting the identification of antiparasitic drugs fro...


Marine natural products as innovative cosmetic ingredients

Fonseca, Sara; Amaral, Mariana Neves; Reis, Catarina Pinto; L, Custódio

Over the course of the last 20 years, numerous studies have identified the benefits of an array of marine natural ingredients for cosmetic purposes, as they present unique characteristics not found in terrestrial organisms. Consequently, several marine-based ingredients and bioactive compounds are under development, used or considered for skin care and cosmetics. Despite the multitude of cosmetics based on mari...


Molecular, morphological and chemical diversity of two new species of Antarctic...

Trentin, Riccardo; Moschin, Emanuela; Lopes, André Duarte; Schiaparelli, Stefano; L, Custódio; Moro, Isabella

The current study focuses on the biological diversity of two strains of Antarctic diatoms (strains IMA082A and IMA088A) collected and isolated from the Ross Sea (Antarctica) during the XXXIV Italian Antarctic Expedition. Both species presented the typical morphological characters of the genus Craspedostauros: cribrate areolae, two “fore-and-aft” chloroplasts and a narrow “stauros”. This classification is congru...


Nutritional and phyto-therapeutic value of the Halophyte Cladium mariscus L. (P...

Rodrigues, Maria João; L, Custódio; Mecha, Débora; Zengin, Gokhan; Cziáky, Zoltán; Sotkó, Gyula; Pereira, Catarina Guerreiro

This work searched for the phyto-therapeutic potential and nutritional value of seeds from the halophyte Cladium mariscus L. (Pohl.), aiming at its use as a source of bioactive ingredients for the food industry. Hence, the nutritional profile, including minerals, of seeds biomass was determined; food-grade samples were prepared, and their phytochemical fingerprinting assessed. Extracts were evaluated for in vit...


The medicinal halophyte frankenia laevis l. (Sea Heath) has in vitro antioxidan...

Rodrigues, Maria João; Jekő, József; Cziáky, Zoltán; Pereira, Catarina Guerreiro; L, Custódio

This work explored the medicinal halophyte Frankenia laevis L. (sea heath) as a potential source of bioactive natural products. In this sense, methanol and dichloromethane extracts were prepared from aerial organs containing flowers, leaves and stems, and were profiled for their chemical composition using high-performance liquid chromatography coupled with electrospray ionization mass spectrometry (HPLC-ESI-MS/...


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