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The microenvironment of pituitary adenomas: biological, clinical and therapeuti...

Marques, Pedro; Silva, Ana Luísa; López Presa, Dolores; Faria, Claudia; Bugalho, Maria João

The microenvironment of pituitary adenomas (PAs) includes a range of non-tumoral cells, such as immune and stromal cells, as well as cell signaling molecules such as cytokines, chemokines and growth factors, which surround pituitary tumor cells and may modulate tumor initiation, progression, invasion, angiogenesis and other tumorigenic processes. The microenvironment of PAs has been actively investigated over t...


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